棘阿米巴性角膜炎行角膜移植术的临床观察  

The treatment of acanthamoeba keratitis with keratoplasty

作　　者：郝静华[1] 吕岚[2] 王廉[1] 

机构地区：[1]北京市普仁医院眼科,北京100062 [2]首都医科大学附属北京同仁医院眼科,北京100730

出　　处：《中国实用眼科杂志》2012年第4期450-452,共3页Chinese Journal of Practical Ophthalmology

摘　　要：目的回顾性分析13例棘阿米巴性角膜溃疡行角膜移植手术治疗的临床效果。方法临床诊断棘阿米巴性角膜炎患者13例，其中6例行板层角膜移植术，7例行穿透性角膜移植术，术后继续应用抗阿米巴药物1～3个月。结果术后随访6个月至2年，感染均得到控制。术后视力情况，LK术后指数的1例，0．02。0．1的3例，0．12～0-3的2例，PK术后小于0．02的3例，0．02—0．1的2例，0．12～0．3的2例。结论棘阿米巴性角膜炎在药物不能控制的情况下，行角膜移植术可有效控制炎症，根据病灶的深度合理选择术式，术后可获得良好的治疗效果。同时术后辅以抗阿米巴药物的治疗可以起到辅助治疗的目的。Objective To determine the surgical indications and effects for acanthamoeba comeal ulcer. Methods Six patients out of 13 had lamellar keratoplasty, while the other 7 patients had penetrating with acanthamoeba keratoplasty. All cases were topically applied anti-ameoba drugs for 1-3 months. Results All 13 patients＇ condition was controlled. The visual acuity of most cases was im- proved. The follow up time was 6-24 months. To the cases with acanthamoeba corneal ulcer which was not easy to be controlled, surgical treatment was used. Conclusions Under the medicine uncontrollable condition of the acanthamoeba keratitis, the cornea transplantation can acquire better treatment effect and can reduce the relapse. The type of surgical operation is selected according to the depth and the range of the disease. The treatment of antiamoeba medicine can raise the purpose of assistance treatment after the surgical operation at the same time.

关 键 词：棘阿米巴性角膜炎 角膜移植术 角膜炎/外科学 

分 类 号：R772.21[医药卫生—眼科]