姜黄油抗真菌作用的超微结构研究  

ULTRASTRUCTURE STUDY ON THE ANTIMYCOTIC EFFECT OF TURMERIC OIL

作　　者：林元珠[1] 谭少波[1] 童汝亭[2] 应国华[3] 李向印[3] 李玉英[3] 

机构地区：[1]河北医学院第四医院皮肤科 [2]河北师大化学系 [3]河北医学院电镜室

出　　处：《中国皮肤性病学杂志》1990年第2期67-69,125-2,共3页The Chinese Journal of Dermatovenereology

摘　　要：本文应用透射电镜对姜黄油的抗石膏样毛癣菌的超微结构进行了研究。其初步结果:正常对照组在电镜下可见孢子呈圈形或椭圆形,中央可见胞核,细胞质中隐约可见板层状膜状结构和颗粒核醣体。细胞壁较厚,分为二层,内层电子密度低,外层电子密度较高。菌丝呈长条形可见中隔。纯姜黄油组和0.1%姜黄油乙醇组可见到细胞壁肿胀,膜的完整性被破坏,细胞质内出现多数空泡或均质化。上述所见与试管内药物敏感试验相符合,初步阐明姜黄油在体外试验中有较强的抗石膏样毛癣菌的作用。This paper presented the ultrastructure study with TEM on the antimy-cotic effect of turmeric oil. The results were as follows: In normal controlgroup, the wall of spore and hyphae of trichophyton mentogrophyte consis-ted of two layers, the outer thick-layer with more electron dense and in-ner with less electron dense. The cells had a large nucleus and was rich incytoplasm, which contained mitochondria, glycogen granules and vacuoles,etc. In pure turmeric oil or 0.1% concentration group, the cell wall wasdestroyed, while the cytoplasm showed homogeneous degeneration. Thesedata suggested that the turmeric oil had relatively strong antifungal effect onT. mentagrophyte in vitro.

关 键 词：姜黄油 真菌 超微结构 

分 类 号：R285.5[医药卫生—中药学]