高分辨率MRI对脑动脉粥样硬化的诊断价值  

Diagnose value of high resolution MRI on cerebral atherosclerosis

作　　者：钱秋平[1] 王苇[1] 李澄[1] 赵义[1] 袁红梅[1] 

机构地区：[1]江苏省扬州市第一人民医院影像科,225000

出　　处：《临床神经病学杂志》2012年第2期107-110,共4页Journal of Clinical Neurology

摘　　要：目的探讨高分辨率MRI(HRMRI)对脑动脉粥样硬化的诊断价值。方法对19例颅内血管狭窄或脑动脉粥样硬化的患者进行MRI、MR血管成像(MRA)和HRMRI检查,并进行图像分析。结果 19例患者共检查了27支大脑中动脉(MCA)。10例患者MRI及MRA检查示有MCA相应支配区域急性脑梗死,其中9例(90%)存在MCA狭窄。9例患者无MCA相应支配区域急性脑梗死,其中6例(67%)有MCA狭窄。HRMRI检查显示,有MCA支配区域急性脑梗死患者与无急性脑梗死患者的MCA狭窄处的血管壁厚度、管腔内径、管腔面积及狭窄率比较,差异无统计学意义。共有27支MCA显示存在明确斑块,每支MCA中均有1个斑块。有14支MCA的斑块显示为稳定斑块的性质,其中12支(86%)MCA中斑块的纤维帽完整,2支(14%)MCA中斑块的纤维帽破裂,未见有脂质核心及斑块内出血;有13支MCA的斑块显示为不稳定斑块的性质,其中2支(15%)MCA中斑块纤维帽完整,2支(15%)MCA中斑块纤维帽破裂,8支(62%)MCA斑块内可见脂质核心,1支(8%)MCA斑块内有出血。结论 HRMRI能清晰显示颅内动脉的管壁结构,弥补常规MRA技术的不足,可较好的评价脑动脉粥样硬化。Objective To investigate the diagnose value of high resolution MRI（HRMRI） on cerebral atherosclerosis.Methods Nineteen patients with intracranial artery stenosis or cerebral atherosclerosis were detected by MRI,MR angiography（MRA） and HRMRI,and the results were analyzed.Results Twenty-seven middle cerebral arteries（MCA） were detected in all the 19 patients.MRI and MRA showed that 10 patients had acute cerebral infarction at corresponding dominate region of MCA,including 9 cases（90%） with MCA stenosis.Nine patients didn＇t have acute cerebral infarction at corresponding dominate region of MCA,including 6 cases（67%） with MCA stenosis.HRMRI showed that the differences of thickness of the arterial wall,lumen diameter,lumen area and stenosis rate between patients with and without acute cerebral infarction at corresponding dominate region of MCA were not statistical significant.The plaques were found in all the 27 MCA,with each MCA 1 plaque.The plaques in 14 MCA were stable,including 12 ones（86%） with integrated fibrous cap and 2 ones（14%） with broken fibrous cap,lipid core and intra-plaque hemorrhage were not found.The plaques in 13 MCA were unstable,including 2 ones（15%） with integrated fibrous cap,2 ones（15%） with broken fibrous cap,8 ones（62%） with lipid core and only one（8%） with intra-plaque hemorrhage.Conclusions HRMRI can clearly display the structure of intracranial arteries wall,make up the deficiency of conventional MRA.It can comprehensively evaluate the cerebral atherosclerosis.

关 键 词：大脑中动脉 动脉粥样硬化 高分辨率MRI 

分 类 号：R743.1[医药卫生—神经病学与精神病学]