微卡联合苦参素治疗慢性乙型肝炎的疗效观察  

Clinical observation on treating chronic hepatitis B with vaccae and oxymatrine

作　　者：雷雨[1] 董薇[1] 郭利琴[1] 赵俊[1] 

机构地区：[1]湖北省房县人民医院感染科,湖北房县442100

出　　处：《中国医药科学》2012年第7期74-75,共2页China Medicine And Pharmacy

摘　　要：目的探讨微卡联合苦参素治疗慢性乙型肝炎的疗效。方法 114例慢性乙型肝炎患者随机分成治疗组52例和对照组52例,观察两组患者肝功能、HBeAg及HBV-DNA的变化情况。结果治疗组的肝功能复常率、HBeAg以及HBV-DNA的阴转率均比对照组要高,差异有统计学意义(P<0.05)。结论微卡与苦参素联合治疗慢性乙肝能提高细胞免疫应答能力,促进肝功能恢复及HBeAg、HBV-DNA的阴转,二者有明显的协同作用。Objective To explore the curative effect of treating chronic hepatitis B（CHB） with vaccae and oxymatrine.Methods 114 cases of CHB patients were randomly divided into the treatment group and control group with 52 cases in each group.Observing liver function,changes of HBeAg and HBV-DNA of the two groups.Results Normalization rate of liver function,negative rate of HBeAg and HBV-DNA in the treatment group are higher than the control group,there is significant difference（P 0.05）.Conclusion Vaccae combined with oxymatrine can improve cell immune response ability while treating CHB.It can also promote the recovery of liver function and the negative rate of HBeAg and HBV-DNA which has obviously synergies.

关 键 词：微卡 苦参素 慢性乙型肝炎 疗效观察 

分 类 号：R575.1[医药卫生—消化系统]