卵巢癌患者血清中TNF、IL-8水平变化及其临床意义  

Changes of Serum TNF and IL-8 Levels and the Clinical Significancein Patients with Ovarian Cancer

作　　者：李卫鹏[1] 沈继录 刘霞秋 陈扣珍 

机构地区：[1]蚌埠医学院附属医院核医学科,233004

出　　处：《放射免疫学杂志》2000年第2期72-73,共2页Journal of Radioimmanology

摘　　要：目的 :探讨卵巢癌患者血清中肿瘤坏死因子及白细胞介素 -8测定的临床意义。方法 :用放射免疫法检测38例卵巢癌患者血清中肿瘤坏死因子(TNF)及白细胞介素 -8(IL -8)。结果 :卵巢癌患者血清中TNF及IL-8水平高于正常人(P<0.01)。结论 :测定卵巢癌患者血清中TNF、IL-8对该病的治疗及预后均有一定意义。Objective To study the clinical significance of determination of serum TNF and IL-8 levels in patients with ovarian cancer. Methods Serum concentrations of TNF and IL-8 from 38 patients with ovarian cancer and 30 healthy individuals were determined by radioimmunoassay. Results The levels of TNF and IL-8 in ovarian cancer patients [(2.16±0.43)μg/L,(0.177±0.054)μg/L] were significantly higher than those in healthy controls [(0.96±0.30)μg/L,(0.090±0.028)μg/L](P<0.01). Conclusions Measarement of TNF and IL-8 levels in patients with ovarian cancer might be clinically helpful for assessing therpeutic effect and prognosis.

关 键 词：肿瘤坏死因子 白细胞介素-8 卵巢肿瘤 

分 类 号：R737.310.2[医药卫生—肿瘤]