溃疡性结肠炎患者血清一氧化氮和TNFα测定  

Detection of serum No and TNFα in patients with ulcerous colonitis

作　　者：郑妙贞[1] 张苏闽[1] 潘仁智[1] 陈若霞[1] 汪义军[2] 

机构地区：[1]南京市中医院,南京210000 [2]南京军区南京总医院解放军普通外科研究所

出　　处：《医学研究生学报》2000年第1期26-27,共2页Journal of Medical Postgraduates

摘　　要：目的 :观察一氧化氮、TNFα与溃疡性结肠炎的关系。　方法 :采用硝酸还原酶法和生物素链亲和素 EL ISA法测定 40例溃疡性结肠炎患者和 40例正常人血清 NO和 TNFα。　结果 :1溃疡性结肠炎患者血清 NO浓度非常显著地高于正常人 (P<0 .0 1) ,阳性率为 85 % ;2溃疡性结肠炎患者 TNFα显著高于正常人 (P<0 .0 5 )。　结论 :血清 NO升高可作为溃疡性结肠炎检测的实验室指标。Objectives:Observe the relationship between NO.TNFα and ulcerous colonitis. Methods:Forty patients suffering from ulcerous colonitis and 40 normal people were tested by nitrate reductase methods and bistin streptavidin. Results:①The percentage of No of the patients were much higher than the normals( P <0.01).The rate of positive was 85%;②The percentage of TNFα of the patients were much higher than the normals( P <0.05). Conclusions:The increase of NO in blood is the sign of suffering from celcerous colonitis.

关 键 词：一氧化氮 肿瘤坏死因子 溃疡性结肠炎 

分 类 号：R574.62[医药卫生—消化系统]