舒尼替尼单药治疗晚期三阴乳癌胸壁转移的初步疗效观察(附1例报告并文献复习)  

SUNITINIB MONOTHERAPY FOR TRIPLE-NEGATIVE BREAST CANCER WITH CHEST WALL METASTASIS:REPORT OF ONE CASE AND REVIEW OF LITERATURE

作　　者：张红军[1] 张立建[1] 刘杰[2] 

机构地区：[1]青岛大学医学院附属医院肿瘤科,山东青岛266003 [2]青岛市市立医院肿瘤科

出　　处：《齐鲁医学杂志》2012年第2期123-124,共2页Medical Journal of Qilu

摘　　要：目的观察舒尼替尼单药治疗胸壁转移的晚期三阴乳癌的有效性和安全性。方法应用舒尼替尼单药治疗蒽环类、紫杉类及培美曲塞治疗无效的三阴乳癌晚期病人1例。结果舒尼替尼单药治疗晚期三阴乳癌胸壁转移有效,毒副作用轻,病人耐受良好。结论舒尼替尼单药可能是体质差的晚期三阴乳癌病人治疗的一种有效的选择。Objective To assess the efficacy and safety of sunitinib monotherapy for triple-negative breast cancer（TNBC） patient with chest wall metastasis. Methods One TNBC advanced patient who failed to response previous anthracycline,docetaxel and pemetrexed therapy was treated with oral sunitinib. Results Monotherapy with sunitinib for this case was effective,with mild side effects and the patient was well tolerated.This case indicated that sunitinib was well tolerated and efficiency. Conclusion Sunitinib monotherapy may be an effective choice for advanced-stage TNBC patients with a poor physical status.

关 键 词：乳腺肿瘤 肿瘤转移 药物疗法 舒尼替尼 

分 类 号：R737.9[医药卫生—肿瘤]