乳腺恶性肿瘤冰冻切片诊断准确率的病理及临床因素研究  

Breast Tumour Diagnostic Accuracy of Frozen Section Pathological and Clinical Factors

作　　者：曾洲红[1] 

机构地区：[1]广东省高州市人民医院病理科,广东高州525200

出　　处：《中国医药指南》2012年第10期29-30,共2页Guide of China Medicine

摘　　要：目的探讨影响冰冻切片诊断乳腺恶性肿瘤的诊断准确率的病理及临床因素。方法回顾我院2010年1月至2011年6月间90例诊断乳腺恶性肿瘤冰冻切片与术后石蜡切片的诊断结果,探讨临床医师取材送检的肿物组织大小对术中冰冻切片诊断准确率的影响,分析造成延迟诊断的病理及临床因素。结果临床医师取材送检组织大小≥2.5cm的诊断准确率明显高于送检组织大小<2.5cm诊断准确率,差异具有统计学意义(0.05≥P>0.01)。结论冷冻切片诊断乳腺恶性肿瘤有其重要意义和较高的准确性。送检肿物组织越大,术中冰冻与术后诊断符合率就越高。延迟诊断可能与送检组织局限、交界性病变和疑难病例诊断困难以及诊断医师经验不足有关。Objective To investigate the impact of intraoperative frozen diagnosis of breast tumour diagnostic accuracy of pathology and clinical factors.Methods Retrospective hospital from January 2010 to June 2011 among 90 cases of frozen section diagnosis of breast cancer diagnosis and postoperative paraffin section results of clinicians drawn from inspection of the tumor tissue the size of the diagnostic accuracy of intraoperative frozen section rate impact analysis resulting in delayed diagnosis of pathological and clinical factors.Results Clinicians drawn censorship organization the size of≥2.5cm diagnostic accuracy was significantly higher than censorship organization the size of 2.5cm diagnostic accuracy,the difference was statistically significant（0.05≥ P〈0.01）.Conclusion Frozen section diagnosis of breast tumour has its significance and high accuracy.Poorer tumor differentiation,tumor tissue greater inspection,intraoperative frozen with the higher rate after the diagnosis.Delay in diagnosis may be limited inspection organization,borderline lesions and difficult to diagnose difficult cases,and lack of experience on medical diagnosis.

关 键 词：乳腺恶性肿瘤 冰冻切片 准确率 病理 临床因素 

分 类 号：R737.9[医药卫生—肿瘤]