以色素性紫癜性皮病为表现的蕈样肉芽肿  

A case of mycosis fungoides presenting as persistent pigmented purpuric dermatosis

作　　者：李薇薇[1] 杨海珍[1] 武玲慎[1] 涂平[1] 

机构地区：[1]北京大学第一医院皮肤性病科,北京100034

出　　处：《临床皮肤科杂志》2012年第5期285-287,共3页Journal of Clinical Dermatology

摘　　要：报告1例以持续性色素性紫癜性皮病为表现的蕈样肉芽肿。患者男,48岁。因双下肢褐色斑3年,逐渐加重偶伴瘙痒就诊。皮肤科检查可见双下肢、腰部、双臀部红褐色瘀点样的斑片,双足背、足侧面及小腿处可见深褐色斑片,轻度苔藓化,双手背、手指背侧亦可见类似皮疹。皮损组织病理示:真皮浅中层淋巴细胞灶状浸润,部分细胞可见异形性和明显的向表皮性。免疫组化检查:CD3(+),CD5(+),D4(+),CD8散在阳性,T细胞受体(TCR)β(+),CD20(-),T细胞胞质内抗原(TIA)1(+)。诊断:蕈样肉芽肿。A case of mycosis fungoides presenting as persistent pigmented purpuric dermatosis is reported. A 48-year-old male presented with eruption on his lower extremities for 3 years, the lesions gradually aggravated and with occasinnally itching. Dermatological examination disclosed erythematous and red-brown petechial patches on his waist, buttocks and lower extremities, and some dark brown pigmented patches on the dorsa of feet and hands with mild lichenifit＇ation. Histopathnlogi- cal examination showed there was focal lymphocytic infihration in the papillaLy and reticular dermis, and some lymphoeytes stlowed atypical and significant epidermotropism, Immunohistochemical investigation showed tumor cells stained positive for CD3,CD5,CD4,CD8, TCRIB, and TIAl,and negative for CD20. Thus mycosis fuugoides was diagnosed.

关 键 词：蕈样肉芽肿 色素性紫癜性皮病 持续性 

分 类 号：R739.5[医药卫生—肿瘤]