小肠间质瘤57例临床分析  

Clinical analysis of 57 cases of small intestine stromal tumors

作　　者：彭树松 崔建芳[2] 刘霆[2] 杨根欢[3] 阳静[2] 冷爱民[2] 

机构地区：[1]深圳市人民医院病理科,广东深圳518020 [2]中南大学湘雅医院消化内科,湖南长沙410008 [3]中南大学湘雅医院普外科,湖南长沙410008

出　　处：《中国医学工程》2012年第2期32-34,共3页China Medical Engineering

摘　　要：目的探讨小肠间质瘤(small intestine stromal tumors,SISTs)的临床特征、诊断及治疗,以提高诊断及治疗水平。方法回顾性总结分析57例小肠间质瘤的临床资料,所有病例均经手术和病理证实。结果 57例患者中男34例,女23例,平均年龄51.7±9.5岁。小肠间质瘤常见的临床表现为:消化道出血、腹痛,好发于空肠和十二指肠,胃镜、超声内镜、增强螺旋CT和双气囊小肠镜检查可以提高检出率。57例均行手术治疗,无围手术期死亡。其中93.0%(53/57)行小肠肿瘤根治术,7.0%(4/57)行姑息手术。术后病理均为小肠间质瘤,其中,极低危5例(8.8%),低危18例(31.6%),中危16例(28.1%),高危(Ⅳ级)18例(31.6%)。随访时间6个月至36个月,3例出现远处转移或局部复发,2例死亡。结论小肠间质瘤无特异性临床症状,合理应用辅助检查可提高小肠间质瘤的术前检出率,其确诊依赖于病理检查,积极手术治疗可以获得良好效果。【Objective】 To analyze the clinical manifestation,diagnosis and treatment of small intestine stromal tumors（SISTs）.【Methods】 The clinical data of 57 SISTs patients treated between January 2008 to December 2010 in our hospital were analyzed retrospectively.All patients were identified by postoperative histopathological examination.【Results】 The patients comprised 34 males and 23 females,with a meanaverage age of 53 years.The major clinical signs included： gastrointestinal bleeding,abdomen pain.The gastrointestinal stromal tumors of the small intestine had predilection in the jejunum and duodenum.The detection rates by fiberoptic endoscopy,endoscopic ultrasound,enhanced spiral CT and Double-balloon enteroscopy were much higher.All patients received surgical operation and no death was found during perioperative period.Among the 57 cases,fifty-three（93.0%） underwent radical operation,and the rest（7.0%） had palliative surgery.Pathology diagnosis was SISTs in all patients.tients underwent complete tumor resection,two did laparotomy only.Among the patient 5 cases were extremely low biological risk（8.8%）,18 at low risk（31.6%）,16 at moderate risk（28.1%） and 18 at high risk（31.6%）.All patients were followed-up from 6 to 36 months.Three of the patients had metastasis or local recurrence,and 2 patients died.Surgical rection is the main treatment.【Conclusion】 There is no special clinical manifestation for SISTs.The detection rate Can be improved by rational auxiliary examinations.Final diagnosis should be based on pathology.The most effective therapy is operation remova1.

关 键 词：间质瘤 小肠 诊断 治疗 

分 类 号：R735.32[医药卫生—肿瘤]