纤支镜活检诊断气管支气管良性肿瘤11例临床病理分析  

Tracheobronchial benign tumour diagnosed by bronchoscopic biopsy: a clinicopathologic analysis of 11 cases

作　　者：何萍[1,2] 姚广裕[3] 顾霞[2] 吴其年[2] 顾莹莹[2] 林云恩[2] 何建行[4] 

机构地区：[1]南方医科大学研究生学院,广州510515 [2]广州医学院第一附属医院病理科,广州510120 [3]南方医科大学南方医院乳腺中心,广州510515 [4]广州医学院第一附属医院胸外科,广州510120

出　　处：《临床与实验病理学杂志》2012年第4期415-418,共4页Chinese Journal of Clinical and Experimental Pathology

摘　　要：目的分析11例气管支气管良性肿瘤的临床病理特征,加深对该类肿瘤的认识,提高确诊率。方法对11例经纤支镜活检诊断为气管支气管良性肿瘤的病例进行回顾性分析。结果 11例中男女比为9∶2,包括气管鳞状上皮乳头状瘤及血管球瘤各1例;支气管颗粒细胞瘤及多形性腺瘤各1例;支气管平滑肌瘤及腺性乳头状瘤各2例;支气管错构瘤3例。不同病理类型的肿瘤表达特异性的免疫组化标记物,影像学检查误诊率较高。结论原发性气管支气管良性肿瘤多见于男性,发生部位以支气管居多。该类肿瘤多数病理类型具有特征性的组织学改变及免疫组化标记物,故纤支镜活检为最可靠确诊手段。为避免误诊临床医师应提高取活检意识。Purpose To improve the understanding and diagnostic accuracy of tracheobronchial benign tumour by analyzing clinicopathologic features of 11 cases.Methods A retrospective analysis was performed on 11 cases of tracheobronchial benign tumour diagnosed by bronchoscopic biopsy.Results Tracheal benign tumors included squamous cell papilloma（1 case） and glomus tumour（1 case）.Bronchial benign tumour included granular cell tumor（1 case）,pleomorphic adenoma（1 case）,leiomyoma（2 cases）,glandular papilloma（2 cases） and hamartoma（3 cases）.The ratio of male to female was 9 ∶2.Specific immunohistochemical markers were expressed in different histological types of the tumors.The incidence of imaging misdiagnosis was high.Conclusions Primary tracheobronchial benign tumor often occurs in bronchi and is more common in men.Bronchoscopic biopsy is the most reliable means of diagnosis because most histological types of tracheobronchial benign tumor have characteristic alterations and can be further confirmed by immunohistochemistry.To avoid misdiagnosis,clinicians should raise the awareness of taking biopsies.

关 键 词：气管肿瘤 支气管肿瘤 良性肿瘤 纤支镜活检 

分 类 号：R734.1[医药卫生—肿瘤]