利用植物生物反应器生产药用蛋白质  

Research progress of producing pharmaceutical proteins by using plant bioreactor

作　　者：李文荣[1] 郑克勤[1] 

机构地区：[1]广东医学院医学遗传学研究室,东莞523808

出　　处：《生命的化学》2012年第2期151-154,共4页Chemistry of Life

基　　金：东莞市科技计划项目资助

摘　　要：植物生物反应器是一种安全、环保、廉价的生产系统。它已成为生产药用蛋白质的理想载体并受到广泛的关注。目前,生物反应器通过靶向表达来提高外源蛋白质产量取得了一定的效果。本文简要介绍了生物反应器的选择,并着重阐述了通过在空间上的定位表达和时间上的诱导表达来提高药用蛋白质产量方面的最新研究进展,同时展望了未来的发展前景。Plant bioreactor is a safe,environment-friendly,and cheap expression system.It is becoming an ideal vehicle to produce pharmaceutical proteins and has been widely concerned.At present,using plant bioreactor through targeted expression to increase the production of exogenous protein has got certain effects.This paper aims at introducing the ways of choosing bioreactor.The research progress of how to improve the production of medical protein through punctually and spatially inducible expression was reviewed.The future prospects were also discussed.

关 键 词：植物生物反应器 药用蛋白 叶绿体 油体 内质网 

分 类 号：Q943.2[生物学—植物学]