益生菌颗粒对便秘和腹泻患者的临床研究  

THE CLINICAL STUDY OF THE EFFECTS OF PROBIOTICS IN PATIENTS WITH CONSTIPATION AND DIARRHEA

作　　者：张片红[1] 吴悦[1] 孟雪杉[1] 孙伟杰[1] 

机构地区：[1]浙江大学医学院附属第二医院,杭州310009

出　　处：《营养学报》2012年第2期147-149,共3页Acta Nutrimenta Sinica

基　　金：浙江大学科研项目(No.H20102695);浙江省重大科技专项计划项目(No.2011C02003)

摘　　要：目的观察益生菌颗粒对便秘与腹泻患者的疗效和安全性。方法采用自身对照试验,77例便秘和87例慢性腹泻患者口服益生菌颗粒30d,记录并量化服用前、后患者的胃肠道症状和不良反应情况。结果口服益生菌颗粒30d后,便秘、腹泻患者有效率分别为为71.4%、77.0%,无不良反应。结论益生菌颗粒可明显改善腹泻和便秘的症状,且安全性高、耐受性好。Objective To observe the efficacy and safety of probiotics on constipation and diarrhea.Method In the self-controlled trial of 30 d,77 patients with constipation and 87 patients with chronic diarrhea were orally administered probiotics particles.Gastrointestinal symptoms and adverse reactions were recorded and quantified before and after administration of the probiotics particles.Results After 30 d oral administration of probiotics,the effective rates for constipation and diarrhea patients were 71.4% and 77.0% respectively without any adverse effect.Conclusion Probiotics particles can improve the symptoms of diarrhea and constipation,and it is safe and well tolerated.

关 键 词：益生菌 便秘 腹泻 

分 类 号：R574[医药卫生—消化系统]