超选择动脉内接触性溶栓治疗急性脑梗死疗效分析  

Analysis of therapeutic effects in acute cerebral infarction with superselective intra-arterial thrombolytic therapy

作　　者：张桂茹 戚春波 

机构地区：[1]蓬莱市人民医院神经内科,山东省265600

出　　处：《中华脑血管病杂志（电子版）》2012年第1期16-18,共3页Chinese Journal of Cerebrovascular Diseases(Electronic Edition)

摘　　要：目的探讨超选择动脉内接触性溶栓治疗急性脑梗死临床效果。方法选取急性脑梗死患者88例,随机分为两组。对照组43例采用常规药物治疗。溶栓组42例采用脑血管造影后,栓塞部位尿激酶局部溶栓治疗;治疗结束后评价临床治疗效果。结果溶栓组患者治疗总显效率、血管总再通率及Barthel指数评分完全恢复率均明显高于对照组,组间比较差异有统计学意义(P<0.05);同时溶栓组患者治疗后美国国立卫生研究院卒中量表(NIHSS)评分明显低于对照组,组间比较差异亦有统计学意义(P<0.05)。结论超选择动脉内接触性溶栓早期治疗急性脑梗死安全、有效,具有临床推广使用价值。Objective To investigate the clinical therapeutic effects of acute cerebral infarction with superselective intra-arterial thrombolytic therapy.Methods 88 patients with acute cerebral infarction were chosen and divided into 2 groups randomly.The clinical therapeutic effects of control group with conventional drug therapy and thrombolysis group with local thrombolytic therapy with urokinase in embolization were evaluated after treatment.Results The rate of total treatment effective,total vascular recanalization and complete recovery on barthel index scores of thrombolysis group were significantly higher than control group（P0.05）.The national institutes of health stroke scale（NIHSS） scores of thrombolysis group was significant lower than control group（P0.05）.Conclusions The early treatment of acute cerebral infarction with superselective intra-arterial thrombolytic therapy is effective,safe,and worthy of clinical application.

关 键 词：超选择 动脉内接触性溶栓 急性脑梗死 

分 类 号：R743.3[医药卫生—神经病学与精神病学]