肠愈宁治疗活动期溃疡性结肠炎疗效观察  

Effect of Changyuning in treating active ulcerative colitis

作　　者：谢晶日[1] 陆振华[1] 刘朝霞[1] 

机构地区：[1]黑龙江中医药大学附属第一医院肝脾胃科,黑龙江哈尔滨150040

出　　处：《中国中西医结合消化杂志》2012年第4期151-153,共3页Chinese Journal of Integrated Traditional and Western Medicine on Digestion

基　　金：教育部春晖计划资助项目(z2009-1-15014)

摘　　要：[目的]观察肠愈宁颗粒治疗活动期溃疡性结肠炎(UC)的临床疗效。[方法]60例患者随机分为2组各30例,治疗组予以中药肠愈宁颗粒口服,10g,早晚分服;对照组予口服美沙拉嗪1.0g/次,4次/d。8周为1个疗程。观察2组患者治疗后主要临床症状、结肠镜下黏膜改善情况及临床疗效。[结果]治疗组总有效率为93.3%,对照组90.0%,2组比较差异无统计学意义(P>0.05)。临床症状改善情况2组比较差异亦无统计学意义(P>0.05)。[结论]肠愈宁颗粒治疗活动期UC疗效显著,与西药美沙拉嗪相当,值得临床推广应用。[Objective]to observe the clinical curative effect of Changyuning in the treatment of active ulcerative colitis. [Methods]Sixty cases were randomly divided into the treatment group and control group,30 cases in each group.The treatment group were treated with oral Chinese medicine Changyuning Particles 10g twice a day,while the control group were given oral Mesalamine 1.0 g four times daily.After 8 weeks＇ treatment,main clinical symptoms,mucous changes as well as the clinical efficacy were observed in both groups. [Results]The total effective rate was 93.3% in the treatment group and 90.0% in the control group,showing no significant difference（P0.05）.There was no remarkable difference in clinical symptoms between the two groups（P0.05）. [Conclusion]Changyuning has similar effect to Mesalamine in treating active ulcerative colitis,and worth more wide clinical application.

关 键 词：结肠炎 溃疡性 肠愈宁 美沙拉嗪 

分 类 号：R574.62[医药卫生—消化系统]