固本调肠汤治疗腹泻型肠易激综合征疗效观察  

Clinical Observation of IBS with diarrhea treated by Guben Tiaochang Tang

作　　者：来要良[1] 杨晋翔[2] 韩海啸[3] 

机构地区：[1]北京中医药大学,2010级博士研究生北京100029 [2]北京中医药大学第三附属医院脾胃病科,北京100029 [3]北京中医药大学东方医院脾胃病科,北京100078

出　　处：《中国中西医结合消化杂志》2012年第4期153-155,共3页Chinese Journal of Integrated Traditional and Western Medicine on Digestion

摘　　要：[目的]观察中药固本调肠汤治疗脾肾阳虚型腹泻型肠易激综合征(IBS-D)的疗效。[方法]将90例患者随机分为2组,各45例,治疗组予固本调肠汤,对照组予马来酸曲美布汀胶囊治疗。治疗4周,采用临床积分差值法,观察IBS-D的总疗效及主要症状疗效。[结果]治疗后,治疗组改善IBS-D主要症状腹痛、大便次数及性状疗效优于对照组(P<0.05);改善疾病的严重度疗效优于对照组(P<0.05)。[结论]以温肾健脾法为组方原则的固本调肠汤对IBS-D的临床疗效明显优于马来酸曲美布汀。[Objective]To explore the effect of Guben Tiaochang Tang in the treatment of irritable bowel syndrome with diarrhea（IBS-D）. [Methods]Ninety patients with IBS-D were randomly divided into the experimental group（n=45）and the control group（n=45）.The experimental group was given Guben Tiaochang Tang,and the control group was only given trimebutine maleate capsule for 4 weeks.The improvement of clinical symptoms such as abdominal pain,form and frequency of stool were evaluated by clinical symptom score. [Results]After 4 weeks＇ treatment,the main symptom scores of both groups were significantly lower than those before the treatment（P0.05）,and the alleviation of IBS-D score of control group was significantly lower than that of experimental group（P0.05）. [Conclusion]Guben Tiaochang Tang is more effective in patients with IBS-D than western medicine.

关 键 词：腹泻型肠易激综合征 脾肾阳虚证 固本调肠汤 温肾健脾法 

分 类 号：R574.62[医药卫生—消化系统]