围手术期输血与先天性巨结肠根治术后感染关系的探讨  

The relationship between perioperative blood transfusion and infectious complications after operations for Hirschsprung's disease

作　　者：李龙[1] 张金哲[1] 王燕霞[1] 刘荫棠[1] 魏临琪[1] 

机构地区：[1]北京儿童医院外科,邮政编码100045

出　　处：《北京医学》2000年第2期67-69,共3页Beijing Medical Journal

摘　　要：目的　了解围手术期输血对先天性巨结肠根治术后感染的影响。方法　从 1 995年 1月至1 997年 4月 ,对 87例择期行先天性巨结肠根治术患儿进行前瞻性研究 ,输血组 61例 ,未输血组 2 6例。结果　 61例输血组患儿中 ,2 0例发生术后感染 ,感染率 3 2 .8%。感染种类包括 :腹腔脓肿 2例 ,切口化脓1 3例 ,支气管周围炎 5例 ,肺炎 3例 ,其中 3例病人患两种感染 ;而未输血组 2 6例患儿中仅 1例腹腔脓肿。输血及输血量与术后感染关系极为密切 ,P值分别为 0 .0 0 2 4和 0 .0 0 73 ;术后感染与性别、年龄、术式、术前贫血、手术时间关系不密切 ,P>0 .0 5。通过多元回归分析示 :感染与输血次数呈正相关。结论　输血增加了先天性巨结肠根治术后的感染率。Objective This study was to investigate the effects of blood transfusion upon postoperative infections after the operations for Hirschsprung's disease Methods This prospective study was carried out on 87 children (average 3 7 years old) who underwent radical operations for Hirschsprung's disease from Jan 1995 to Apr 1997 The patients were divided into two groups:blood transfusion group(61 cases)and non blood transfusion group(26 cases) Results 20 of 61 patients(32 8%) in blood transfusion group suffered from postoperative infections which included wound sepsis 15 cases,bronchisis 5 cases,pneumonia 3 cases Among them 2 patients had two kinds of infections However,only 1 patient (3 8%)in the non blood transfusion group had wound infection The statistical analysis demonstrated that the postoperative infections significantly associated with blood transfusion and the blood volume transfused( P =0 0024 and 0 0073 respectively) Whereas the infections had no significant correlation with sex,age,surgical procedures,preoperative anemia and operating time Conclusions Perioperative blood transfusion can increase the risk of infectious complications after the radical operation for Hirschsprung's disease

关 键 词：输血 先天性巨结肠 围手术期 术后 感染 

分 类 号：R656.9[医药卫生—外科学] R619[医药卫生—临床医学]