胃癌患者术后早期肠内营养与肠外营养疗效比较  

Comparison on the effect of early enteral nutrition and parenteral nutrition applied on patient undergoing gastric tumor operation

作　　者：朱旭峥[1] 李峰[1] 

机构地区：[1]空军总医院营养科,北京100142

出　　处：《武警医学院学报》2012年第2期92-94,共3页Acta Academiae Medicinae CPAPF

摘　　要：【目的】研究肠内营养对胃癌患者术后胃肠功能恢复的影响。【方法】胃癌患者76例,随机分为肠内营养组（EN）和肠外营养组（PN）,每组38例。术后均给予营养支持7 d。观察两组腹胀、腹泻、恶心、呕吐、排便等情况,以及血清的白蛋白、血红蛋白、前白蛋白、AST、ALT、肌酐水平变化。【结果】PN组的平均肛门排气时间为5.8 d,EN组的平均肛门排气时间为4.1 d,两组差异有统计学意义（P〈0.05）。PN组平均排便时间为4.6 d,EN组平均排便时间为3.2 d,两组差异有统计学意义（P〈0.05）。术后第4天时,两组的白蛋白、血红蛋白、前白蛋白较术前1 d明显下降,PN组和EZ组之间差异无统计学意义（P〉0.05）。EN组术后第4~8天白蛋白、血红蛋白、前白蛋白上升幅度明显高于PN组,差异均具有统计学意义（P〈0.05）。术后第8天,两组ALT和肌酐差异无统计学意义（P〉0.05）,AST差异有统计学意义（P〈0.05）。【结论】胃癌患者术后早期肠内营养安全可行,能够早期恢复肠道功能,优于肠外营养。【Objective】To evaluate the early application of enteral nutrition support in patients undergoing gastric tumor operation.【Methods】76 cases of gastric after operation were divided into two groups,enteral nutrition group and parenteral nutrition group.They were supported for 7 days on enteral/ parenteral nutrition after operation.Abdomen distention,diarrhea,nausea,vomiting and defecation were observed.Albumin、hemoglobin、prealbumin、AST、ALT and creatinine were measured.【Results】Average time of exhausting by anus of PN group was 5.8±1.4 days and EN group was 4.1±0.8（P 0.05）.From 4~8 days after operation,albumin,hemoglobin,prealbumin of EN group had a great range of increase than PN group（P 〈 0.05）.8 days after operation,ALT and creatinine level of two group had no significant difference,but AST was significant.【Conclusion】Early application of enteral nutrition in patients undergoing gastric tumor operation can maintain nutritional state,promote gastric functional recovery.It is better than parenteral nutrition..

关 键 词：胃癌 肠内营养 肠外营养 功能恢复 

分 类 号：R735.2[医药卫生—肿瘤]