液化碘油混合无水乙醇栓塞治疗小肝癌的临床研究  

Clinical research of embolization with liquefied lipidol and absolute ethyl alcohol in treatment of small hepatocellular carcinoma

作　　者：独建库[1] 李冠海[1] 何伟华[1] 刘献儒[1] 马小桔[1] 

机构地区：[1]解放军第150医院介入科,河南洛阳471031

出　　处：《临床军医杂志》2012年第2期382-384,共3页Clinical Journal of Medical Officers

摘　　要：目的分析超液化碘油与无水乙醇混合后栓塞治疗小肝癌的临床疗效,探讨治疗小肝癌的新方法。方法对经彩超CT或MRI检查发现并经病理证实的小肝癌患者88例共126个病灶,进一步行肝动脉造影,经数字减影血管造影(DSA)证实后,对小肝癌供血动脉行超选择性插管,并以超液化碘油混入无水乙醇(1:0.5)对发现的126个小肝癌病灶充分栓塞。结果 88例患者共126个小肝癌病灶全部行超选择性插管栓塞术,术后无严重并发症发生.术前病灶直径0.8～3.0 cm,平均直径2.75 cm,术后3月复查,肿瘤完全消失16例,72例肿瘤不同程度缩小,肿瘤平均直径1.45 cm。术后1、3、5年复发率分别为17%(15/88)、25%(22/88)、36%(32/88)。术后1、3、5年生存率分别为100%(88/88)、86%(76/88)、68%(60/88)。结论超液化碘油混合无水乙醇栓塞治疗小肝癌疗效显著,术后并发症少,术后复发率低于外科手术治疗,可作为治疗小肝癌的选择方法之一。Objective To analyze the clinical effects of embolization with ultra liquefied lipidol and absolute ethyl alcohol in treatment of small hepatocellular carcinoma,and discuss the new methods for treating small hepatocellular carcinoma.Methods 88 cases with 126 lesions which were diagnosed as small hepatocellular carcinoma by color Doppler ultrasound or MRI received hepatic arteriography.After that was confirmed by digital subtraction angiography（DSA）,ultra selective catheterization was performed on feeding artery of small hepatocellular carcinoma,embolization with ultra liquefied lipidol and absolute ethyl alcohol（1：0.5） was used in treating 126 lesions of small hepatocellular carcinoma.Results All cases were treated by ultra selective catheterization,no major complications were found.Before the embolization,the diameter of tumors was 0.8-3.0 cm,average diameter was 2.75cm.At 3 months after operation,the tumors completely disappeared in 16 cases,shrank in 72 cases,average diameter was 1.45cm.The 1,3 and 5 years recurrence rate were 17%（15/88）,25（22/88）,36（32/88）,and the survival rates were 100%（88/88）,86%（76/88）,68%（60/88）,respectively.Conclusion Embolization with ultra liquefied lipidol and absolute ethyl alcohol in treatment of small hepatocellular carcinoma is effective with less complication and the recurrence rate is less than surgical operation,it can be used as one of the choice of treatment of small hepatocellular carcinoma.

关 键 词：小肝癌 超液化碘油 无水乙醇 栓塞术 

分 类 号：R735.7[医药卫生—肿瘤]