麻痹性痴呆的临床特点(附1例报告)  

Clinical features of general paresis of insane(report of 1 case)

作　　者：陈秀[1] 李晓红[1] 张泽兰[1] 罗华[1] 李小刚[1] 

机构地区：[1]泸州医学院附属医院神经内科,四川泸州646000

出　　处：《泸州医学院学报》2012年第2期203-205,共3页Journal of Luzhou Medical College

摘　　要：目的:探讨麻痹性痴呆(general paresis of insane,GPI)的临床特点,以及实验室与影像学检查的诊断价值。方法 :回顾性分析1例经临床确诊的麻痹性痴呆患者的临床资料,并结合文献进行分析。结果 :主要临床表现为精神和认知障碍、震颤、肌张力增高等,血清及脑脊液螺旋体血球凝集试验阳性,头颅磁共振影像为大脑半球重度脑萎缩。结论:麻痹性痴呆临床表现多样,误诊率高;诊断主要依据临床表现、实验室与影像学改变。Objective：To explore the clinical features of general paresis of insane（GPI） and diagnostic value of laboratory and neuroimaging examinations.Methods：The clinical data of 1 patient with GPI were analyzed retrospectively and the pertinent literatures were reviewed.Results：The main clinical manifestations were psychiatric and cognitive symptoms,tremor,and hypermyotonia.Treponema haemocyanin agglutination test in serum and cerebrospinal fluid（CSF） were positive.Cranial MRI showed servere cerebral atrophy.Conclusion：The clinical manifestations of GPI are varied and misdiagnosis rate of GPI is high.The diagnosis of GPI mainly depends on clinical manifestations,laboratory test,and neuroimaging examination

关 键 词：神经梅毒 麻痹性痴呆 

分 类 号：R759.1[医药卫生—皮肤病学与性病学]