内镜下氰基丙烯酸酯注射法与套扎法治疗胃底食管静脉曲张的Meta分析  

Cyanoacrylate versus ligation in the treatment of gastroesophageal varices: One Meta-analysis

作　　者：熊小强[1] 胡旭民[2] 凌小婷[2] 黄开红[1] 

机构地区：[1]中山大学孙逸仙纪念医院消化内科,广州510120 [2]中山大学中山医学院医学系

出　　处：《中华普通外科学文献（电子版）》2012年第2期49-54,共6页Chinese Archives of General Surgery(Electronic Edition)

摘　　要：目的对于食管胃底静脉曲张,目前国际上经典方法为套扎法,随着组织胶水被广泛应用临床,氰基丙烯酸酯被较多用在内镜下该病的硬化治疗。本文旨在对比两者在治疗食管胃底静脉曲张的优劣。方法通过数据统计、定性分析、异质性分析、Meta分析,偏倚分析对已获得文献进行分析。结果两组间急性出血止血率、根治率和死亡率差异无统计学意义,再出血率套扎组高于胶水组,食管静脉曲张组并发症胶水组高于套扎组。结论氰基丙烯酸酯注射法和套扎法是治疗胃食管静脉曲张的有效方法。治疗胃底静脉曲张时注射法较套扎法再出血率低而并发症发生率相似,所以首选注射法。治疗食管静脉曲张时对于复发倾向较高的患者,在权衡并发症的情况下可以考虑使用注射法。Objectives The classic therapeutic method of gastroesophageal variees is ligation. Cyanoacrylate injection is rising up to be a better way to cure these very disease in a few past years. This article is try to find the advantage of cyanoaerylate injection. Methods Data statistics, qualitative analysis, quantitative analysis, Meta analysis, and bias analysis were used to evaluate acquired articles. Results No statistical significance was found on hemostatie rate, eradication rate and mortality between the two group. The rebleeding rate of ligation group was higher than cyanoacrylate injected group, and complications in the cyanoacrylate injected group was fewer than ligation group in esophageal variees group. Conclusions Cyanoacrylate injected method is generally better than ligation because of lower rebleeding rate. In the case of managing patients with higher rebleeding tendency, Cyanoacrylate may be a better way.

关 键 词：氰基丙烯酸酯 套扎法 胃底食管静脉曲张 META分析 

分 类 号：R575.2[医药卫生—消化系统]