完全性充填法经肝动脉化疗栓塞术在肝癌介入治疗中的应用(附22例报告)  

The application of completely-filling method transcatheter arterial chemoembolization in the interventional treatment of liver cancer :Report of 22 cases

作　　者：高长启[1] 庄建良[1] 汪荣灿[1] 西洛次仁[1] 

机构地区：[1]福建医科大学附属泉州第一医院放射科,泉州362000

出　　处：《福建医药杂志》2012年第2期94-96,共3页Fujian Medical Journal

摘　　要：目的探讨完全性充填法经肝动脉化疗栓塞术(TACE)在肝癌介入治疗中的可行性及安全性并与传统方法的TACE进行比较。方法选择肝右叶肝癌患者22例,采用超选择插管技术,对肿瘤的供血动脉行完全性充填法化疗栓塞术,即于癌灶灌注化疗后,以超液态碘油—化疗药混悬液完全充填癌灶,至癌灶周围肝组织的门静脉小分支出现碘油沉积为止。结果本组病例短期内复查CT显示,瘤灶显著缩小(≥50%)且无新病灶出现18例(81.8%);中度缩小(50%～25%)且无新病灶出现4例(18.2%)。除1例并发肝癌破裂死亡外,其余21例均在随访中,目前已随访2、3、4年的病例分别为21、18、2例。结论完全性充填法TACE对于肝癌是安全有效的,近期疗效较传统方法为佳,可望提高其远期疗效。Objective To investigate feasibility and safety of completely filling method transcatheter arterial chemoembolization （TACE） in the interventional treatment of liver cancer, comparing to traditional TACE. Methods Twenty-two cases of right lobe liver cancer were selected. Completely-filling method TACE were performed by super selective intubation technology to embolize the nutritional artery of the tumor with liquid iodine oil-chemotherapy drug solution, until the tumor focus was com- pletely filled and iodine oil filling was seen in the small branches of portal vein. Results Short review of CT showed： 〉50% tumor size reduction and no new tumor focus was seen in 81.8% （18/22） cases; 50%-25% tumor size reduction and no new tumor focus were seen in 18.1% （4/22） cases. Only one case died of tumor rupture, the other 21 cases have been followed up, among them 21/22 cases have been follow up for two years, 18/22 have been followed up for 3 years, and 2/22 have been followed up for 4 years. Conclusion Completely- filling method TACE is safe and effective for the treatment of liver cancer. This new method is better than traditional method in short term and is expected to increase its effect in long term.

关 键 词：癌 肝细胞 肝动脉 化疗栓塞 碘油 

分 类 号：R735.7[医药卫生—肿瘤] R459.9[医药卫生—临床医学]