左心室结构功能异常与脑梗死发病的关系分析  

Analysis on Correlation Between Left Ventricular Structure and Function Abnomalites and Cerebral Infarction

作　　者：陈研修[1,2] 王雁[3] 

机构地区：[1]青岛大学医学院,266003 [2]山东省聊城市人民医院脑科医院 [3]青岛大学医学院附属医院神经内科,266003

出　　处：《中国老年保健医学》2012年第2期15-17,共3页Chinese Journal of Geriatric Care

摘　　要：目的研究左心室结构功能异常与脑梗死发病的关系。方法选择100例急性脑梗死患者及100例健康体检者进行对照,应用超声心动图检查仪测量患者左心室及主动脉根部内径等相关参数,测量血压,检测患者血糖、血脂及血清脑钠肽水平。统计两组数据,分析其差异性。结果脑梗死组患者LDL-C、TG水平、收缩压与舒张压高于对照组(P<0.05或P<0.01)。脑梗死组主动脉根部内径、左室后壁及室间隔厚度、左室心肌质量指数较对照组有增加,(P<0.05或P<0.01)。脑梗死组每搏输出量、心输出量、射血分数、E/A比值均较对照组减低(P<0.05或P<0.01)。脑梗死组BNP定量高于对照组(P<0.05)。脑梗死组左室后壁、室间隔厚度增加、主动脉根部内径扩大,射血分数及E/A比值降低和BNP定量升高的发生率高于对照组(P<0.05或P<0.01)。结论心脏结构和功能异常与脑梗死的发病存在明显相关性,研究数据显示二者可能存在因果关系。积极调整生活方式、控制血压,防止心肌重构和心功能下降,对脑梗死的预防极其重要的意义。Objective To study the correlation between left ventricular structure and function abnormalities and cerebral infarction.Methods 100 cases of acute cerebral infarction patients and 100 healthy subjects were included in this study.Blood pressure,lipids,glucose,serum brain natriuretic peptide（BNP）levels,left ventricular and aortic root diameter and other parameters were recorded.The differences of the two sets of data were analyzed.Results Patients with cerebral infarction group,low-density lipoprotein（LDL-C）,triglyceride（TG）levels were significantly higher than that of control group（P0.01,P0.05）.Patients with cerebral infarction group,Systolic and diastolic blood pressure were significantly higher than that of control.group（P0.01）.Patients with cerebral infarction group,Aortic root diameter,left ventricular posterior wall thickness,interventricular septum thickness, left ventricular mass index were higher than that of control group（P0.01）.The stoke volume,cardiac output and ejection fraction in infarction group were lower than those in control group（P0.05或P0.01）.In infafction group BNP quantitatively higher that in control group（P0.05）.cerebral infarction group E/A ratio lower than control group（P0.05）.In infafction group left ventricular posterior wall,interventricular septum thickness increased,the expansion of the aortic diameter,ejection fraction and E/A ratio decreased and BNP quantitative increase in occurrence was higher than in control group（P0.05或P0.01）.Conclusion Abnormal cardiac structure and function were significantly correlated with cerebal infarction.The study data show that the two may be a causal relationship.Actively adjust the way of life,the reasonable control of blood pressure to prevent myocardiac remodeling and heart dysfunction of great importance for the prevention of cerebral infaction.

关 键 词：左心室结构 功能障碍 脑梗死 相关性 

分 类 号：R743.3[医药卫生—神经病学与精神病学]