跨声门癌局部生长扩展的组织病理学特点及其临床意义  

Histopathological Characteristics of Local Invasiveness of Transglottic Cancer and its Clinical Significance

作　　者：曹志伟[1] 潘子民[1] 费声重[1] 关超[1] 于刚[1] 

机构地区：[1]中国医科大学第一临床学院耳鼻咽喉科,沈阳110001

出　　处：《中国医科大学学报》2000年第2期135-136,共2页Journal of China Medical University

摘　　要：目的 :探讨跨声门癌局部浸润扩展的组织病理学特点及其临床意义。方法 :5 0例跨声门癌喉全切除标本制成连续切片 ,HE染色 ,光镜下观察。结果 :全部病例均系主体位于喉室或以喉室为中心。浸润方式以粘膜下深层浸润为主 ,占 90 % (45 / 5 0 )。跨声门癌向外早期侵入声门旁间隙 ,并沿该间隙以基本均等态式纵向跨区浸润扩展。结论 :跨声门癌原发喉室 ,其局部浸润扩展的组织病理学特点及临床表现均不同于其它类型喉癌 ,应列为单独一型。Objective: To explore the histopothological characteristics of local invasiveness of transglottic cancer and its clinical significance. Methods: Fifty total laryngectomy specimens of transglottic carcinoma were subject to whole organ serial section, HE staining, and microscopic observation. Results: The main lesion of all cases was in the ventricle or the ventricle was the center of the lesion. Deep submucosal invasion was the major way of spreading in transglottic carcinoma, its rate was 90% (45/50). Transglottic carcinoma invaded paraglottic space early and spreaded through the space in a way that equally involved the supraglottic and glottic regions. Conclusion: Transglottic carcinoma originates from the ventricle. Its histopathological characteristics and clinical expression are different from those of other types of laryngeal carcinoma. Transglottic cancer should be taken as one specific type.

关 键 词：喉肿瘤 病理学 肿瘤浸润 跨声门癌 

分 类 号：R739.650.2[医药卫生—肿瘤]