种痘样水疱病样皮肤T细胞淋巴瘤  

Hydroa vacciniforme-like cutaneous T-cell lymphoma

作　　者：段紫钰[1] 曾学思[1] 

机构地区：[1]中国医学科学院北京协和医学院皮肤病研究所,南京210042

出　　处：《国际皮肤性病学杂志》2012年第3期197-199,共3页International Journal of Dermatology and Venereology

摘　　要：种痘样水疱病样皮肤T细胞淋巴瘤是近年来被逐渐认识到的一种与EB病毒相关的少见淋巴瘤，多见于儿童和青少年，主要累及面部和四肢，表现为丘疹、丘疱疹和水疱，随后出现坏死、溃疡、结痂，最后留下痘疮样瘢痕。本病临床表现独特，确诊主要依靠组织病理检查及免疫组化。目前尚无统一有效的治疗方案，报道的多数病例采用化疗，但疗效不一。Hydroa vacciniforme-like cutaneous T-cell lymphoma is a rare subtype of cutaneous T cell lymphoma identified in the past few years. The association between this condition and Epstein Barr virus （EBV） infection has been gradually recognized. It mainly affects children and teenagers with the involvement of face and extremities. The clinical manifestations of this entity are distinct, and lesions usually begin with papules, papulovesicles, vesicles, subsequently develop into necrosis, ulcer and crusts, and heal with varioliform scarring. The diagnosis is mainly based on histopathology and immunohistochemistry. At present there is no uniform and effective treatment. Most reported cases were managed by chemotherapy, but the efficacy varied.

关 键 词：牛痘样水疱症 淋巴瘤 T细胞 疱疹病毒4型 人 

分 类 号：R739.5[医药卫生—肿瘤]