颅眶沟通性肿瘤颅眶重建及围手术期处理  

SKULL BASE RECONSTRUCTION AND PEROPERATIVE TREATMENT FOR CRANIO-ORBITAL TUMORS

作　　者：蒋艳[1] 刘家刚[1] 范学政[2] 蔡博文[1] 

机构地区：[1]四川大学华西医院神经外科,成都610041 [2]广西中医学院附属瑞康医院神经外科

出　　处：《中国修复重建外科杂志》2012年第5期567-570,共4页Chinese Journal of Reparative and Reconstructive Surgery

摘　　要：目的总结颅眶沟通性肿瘤切除术中颅眶重建方法及围手术期护理经验。方法 2008年4月-2011年4月,收治35例颅眶沟通性肿瘤患者。男21例,女14例;年龄17～73岁,平均46.3岁。以眼眶胀痛为首发症状者13例,视力下降12例,眼球突出或眼位不正5例,头痛、头晕2例,复视2例,眼球搏动1例。术中切除病变后采用自体骨片及钛网、额骨骨膜瓣、人工硬脑膜、医用耳脑胶等材料进行颅眶重建,术后重视颅内压管理并预防并发症发生。结果术后3 d,MRI检查示肿瘤全切除30例,次全切除3例,大部切除2例。无手术相关死亡发生。术后1周内发生脑脊液眼漏1例及术区感染2例,分别经腰大池持续引流10 d及抗生素治疗后治愈。患者均获随访,随访时间6～36个月,平均18个月。9例视力下降者术后1个月好转;眼眶胀痛者术后2周内明显缓解;眼球突出或眼位不正及眼球搏动等症状术后均消失。27例良性肿瘤患者24例痊愈,随访期间无复发;8例恶性肿瘤患者18个月内复发6例,行二次手术或放疗,其中2例于术后24个月死于肿瘤所致脑疝及呼吸循环衰竭。无眼球凹陷、搏动性突眼、颧部塌陷等并发症发生。结论采用自体骨片及钛网、额骨骨膜瓣、人工硬脑膜、医用耳脑胶等材料进行颅眶沟通性肿瘤切除后颅眶重建,具有稳固可靠、操作简便、易达解剖重建等特点,配合围手术期护理,可以取得较好手术效果。Objective To investigate the peroperative treatment of cranio-orbital tumors and the method of the reconstruction of the skull base. Methods Between April 2008 and April 2011, 35 patients with cranio-orbital tumor were treated. There were 21 males and 14 females, aged 17-73 years （mean, 46.3 years）. The first symptoms were orbital pain in I3 cases, hypopsia in 12 cases, exophthalmos or abnormal eye position in 5 cases, headache and dizziness in 2 cases, diplopia in 2 cases, and pulsating eyeball in 1 case. Some of the patients needed resecting the zygomatic arch, superciliary arch, and orbit roof. The autogenous bone, titanium net, frontal bone periosteum, biogel, and artificial meninges were used to reconstruct the skullbase. Results Tumors were resected by one-stage operation, and the anterior skull bases were reconstructed. Postoperative MRI indicated that total removal of tumors was achieved in 30 cases, subtotal in 3 cases, and partial in 2 cases at 3 days. There was no operative death. Cerebrospinal rhinorrhea and infection occurred at 1 week in 1 and 2 cases respectively, and were cured after lumbar drainage and antibiotics. The patients were followed up 6 to 36 months （mean, 18 months）. In patients having hypopsia, the visual function was improved in 9 cases at 1 month; in patients having orbital pain, pain relief was achieved at 2weeks after operation; in patients having exophthalmos or abnormal eye position and pulsating eyeball, sympotoms disappeared after operation. In 27 patients with benign tumor, 24 were cured, without recurrence during follow-up; in 8 patients with malignant tumor, 6 had recurrence within 18 months and underwent second operation or radiotherapy, 2 relapsed cases died of cerebral hernia and respiratory circulating failure at 24 months after operation. No complication of enophthalmos, pulsating exophthalmos, or collapse of zygomatic region occurred. Conclusion Using the autogenous bone, titanium net, frontal bone periosteum, biogel, and artificial meninges to reconstruct the

关 键 词：颅眶沟通性肿瘤 颅眶重建 围手术期处理 

分 类 号：R739.4[医药卫生—肿瘤]