磷酸锌矿化处理胶原膜抗牙龈卟啉单胞菌的实验研究  

Anti-Porphyromonas gingivalis effects of zinc phosphate mineralized collagen membranes

作　　者：李婧[1,2] 廖旭辉[1,2] 陈卓凡[1,2] 

机构地区：[1]中山大学光华口腔医学院.附属口腔医院种植科,广东广州510055 [2]广东省口腔医学重点实验室,广东广州510080

出　　处：《临床口腔医学杂志》2012年第5期262-265,共4页Journal of Clinical Stomatology

基　　金：国家自然科学基金面上项目(30973355);广东省自然科学基金(S2011010004978)

摘　　要：目的:研究使用磷酸锌矿化处理后的胶原膜的抗菌性能。方法:将胶原膜浸泡于含磷酸锌的矿化液中,不间断搅拌3天后取出,双蒸水冲洗,冷冻干燥。通过测量胶原膜在接种了牙龈卟啉单胞菌培养皿上的抑菌环大小评价其抗菌性能。结果:磷酸锌矿化处理后的胶原膜相比未经任何处理的胶原膜表现出明显的抗牙龈卟啉单胞菌能力。结论:磷酸锌矿化处理后的胶原膜具有良好的抑制牙龈卟啉单胞菌生长的性能。Objective：To study the antibacterial effects of zinc phosphate mineralized collegen membranes.Method：Collegen membrane are cut into sections and incubated in zinc phosphate solution,then stir the solution using a magnetic stirrer.After 3 days,the zinc phosphate mineralized membranes were rinsed in double-distilled water and dried by a freezer dryer.Porphyromonas gingivalis are prepared,and the bacteriostatic rings around the sections in the plates are measured to reflect the antibacterial effects.Result：Compared to untreated collegen membranes,zinc phosphate mineralized collegen membranes demonstrate obvious bacteriostatic rings.Conclusion：Zinc phosphate mineralized collegen membranes have excellent antibacterial effects.The result of the present research may improve the outcome of the Guided Bone Regeneration therapy.

关 键 词：胶原膜 磷酸锌 牙龈卟啉单胞菌 

分 类 号：R781.4[医药卫生—口腔医学] R780.2[医药卫生—临床医学]