肠道NK/T细胞淋巴瘤4例诊治分析  

Intestinal primary malignant NK/T-cell lymphoma: report of four cases

作　　者：石玉龙[1] 李辰生[1] 靖昌庆[1] 刘洪俊[1] 李乐平[1] 

机构地区：[1]山东大学附属省立医院胃肠外科,山东济南250021

出　　处：《中国现代普通外科进展》2012年第5期348-351,共4页Chinese Journal of Current Advances in General Surgery

基　　金：山东省优秀中青年科学家科研奖励基金计划(BS2010YY060);山东省自然科学基金资助项目(Y2007C102)

摘　　要：目的:探讨肠道NK/T细胞淋巴瘤的临床特点、诊断及治疗。方法:回顾性分析4例肠道NK/T细胞淋巴瘤的临床资料,对其发病特点、临床表现、实验室检查、诊断和治疗方法进行总结分析。结果:3例为小肠NK/T细胞淋巴瘤,CD45RO(+),CD3(+),CD56(+),CD20(-),TIA(-)。1例为结肠NK/T细胞淋巴瘤,CD45RO(+),CD3(+),CD56(+),CD20(-),TIA(+)。4例患者术后分别存活61、58、14、7 d。结论:肠道NK/T细胞淋巴瘤确诊需依赖术后病理组织学及免疫组织化学检查,早期诊断、尽早实施合理的治疗是降低死亡率的关键。Objective： To study the clinical features, diagnosis and treatment of intestinal pri- mary malignant NK/T-cell lymphoma. Methods： The clinical data of 4 patients with primary malig- nant NK/T-cell lymphoma in the intestine admitted to our hospital from 1998 to 2008 were viewed. Results： Three cases were diagnosed as primary malignant NK/T-cell lymphoma in small intestine and 1 case was in colon by pathology. All 4 cases died respectively, 61,58,14 and 7 days after exploratory surgery ,of possible recurrent perforation. Conclusion： Postoperative pathology and immunohistochemical examination remain the mainstay for final diagnosis. The prognosis is dependent on early diagnosis and treatment.

关 键 词：肠道自然杀伤/T 细胞淋巴瘤 诊断 治疗 

分 类 号：R735.3[医药卫生—肿瘤] R733[医药卫生—临床医学]