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机构地区:[1]福建医科大学教学医院,福建省肿瘤医院放疗科,福建福州350014
出 处:《中国癌症杂志》2011年第12期913-919,共7页China Oncology
基 金:福建省科技厅重点项目(No:2009Y0013)
摘 要:鼻咽癌为放射剂量相关性恶性肿瘤,放射治疗是鼻咽癌的首选治疗方法。调强放射治疗作为精确的放疗技术为提高剂量、保护周围正常组织提供了可能,国内外多家放疗中心的研究结果已证实调强放疗可提高鼻咽癌局部控制率。然而,当前对鼻咽癌的亚临床靶区(clinical target volume,CTV)的界定尚未达成共识,本文通过回顾国内外鼻咽癌CTV定义的发展过程,探讨未来缩小鼻咽癌靶区定义的发展方向和模式。Radiation therapy is the mainstay treatment modality for nasopharyngeal carcinoma (NPC), and the outcome is well associated to radiation dose, As a precise radiation technology, intensity-modulated radiotherapy (IMRT) offers the possibility of improving survival and simultaneously protect the surrounding normal tissue. The improvement of local control by IMRT has been well confirmed by a number of studies form domestic and abroad. However, the selection and definition of clinical target volume (CTV) for nasopharyngeal carcinoma has not yet reached a consensus. This article aimed to discovery the direction and mode for future research of reducing the treatment volume by reviewing the domestic and international development of CTV.
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