微生物酯酶的研究进展  

The Research Progress of Microbial Esterases

作　　者：张敏文[1] 刘悦[1] 李荷[1] 

机构地区：[1]广东药学院基础学院生化与分子生物系,广东广州510006

出　　处：《广东第二师范学院学报》2012年第3期66-71,共6页Journal of Guangdong University of Education

基　　金：国家自然科学基金资助项目(30570055);广东省科技攻关项目(2009B020313005);广东省自然科学基金博士启动基金资助项目(9451022401003873);广东药学院博士启动基金资助项目(2006JCX06)

摘　　要：微生物酯酶是一种广泛应用于食品、医药、精细化工等领域的工业化酶,特别是近年来随着手性化合物的深入研究,酯酶作为手性化合物拆分的高效催化剂,而微生物的来源又十分广泛,因此微生物酯酶成为研究热点.从组成及来源、产酯酶微生物的筛选、微生物酯酶的基因克隆以及微生物酯酶的应用等几方面对微生物酯酶进行综述,微生物酯酶已经在食品加工、精细化工、手性化合物拆分、环境治理中有所应用,随着研究的深入,酯酶的工业化生产及其在各领域的应用将会逐步实现.Microbial Esterases play an important role in food industry, medicine industry, industry of fine chemicals and so on. In recent years, with thorough research of chiral compounds, esterase was a high-effective catalys for chiral resolution, and microbial sources is very extensive, so microbial esterases become research focus. This paper summarized many aspects in research progress of microbial esterases, including the composition and the source, screening of microbial esterase-producing strains, the gene cloning of microbial esterases, and the application of microbial esterases. Microbial esterase had already applied in food processing, fine chemical industry, chiral compounds and environmental treatment. With the development of research, the industrial production of microbial esterase and its application in various fields will gradually realize.

关 键 词：微生物酯酶 应用 手性拆分 

分 类 号：Q556[生物学—生物化学]