间苯三酚治疗急性胃肠炎所致腹痛疗效观察  

Phioroglucinol effectively alleviates abdominal pain in acute gastroenteritis

作　　者：杨爱芳[1] 张博佳[1] 尤态[1] 韩建红[1] 韦松华[1] 

机构地区：[1]同济大学附属第十人民医院感染科,200072

出　　处：《中华全科医师杂志》2012年第6期452-454,共3页Chinese Journal of General Practitioners

摘　　要：为评价间苯三酚注射液治疗急性胃肠炎所致腹痛的疗效及安全性，选取本院300例急性胃肠炎所致腹痛的患者，随机分为治疗组和对照组各150例，分别给予间苯三酚和山莨菪碱静脉滴注，采用疼痛视觉模拟评分法对治疗前及治疗后两组患者的腹痛强度进行评估，同时记录其不良反应。结果显示，治疗后1h，两组患者的腹痛强度均较治疗前明显降低（P〈0．01）；治疗组和对照组的治疗有效率分别为84．1％（126／150）和80．0％（120／150），但治疗组的不良反应发生率明显低于对照组（均P〈0．01）。提示间苯三酚能有效缓解急性胃肠炎患者的腹痛，且安全性较高。The aim of the study was to evaluate the efficacy and safety of phloroglucinol in treatment of abdominal pain caused by acute gastroenteritis. Three hundred patients with acute abdominal pain were randomly assigned to receive 80 mg intravenous infusion of phloroglucinol injection （treatment group, n = 150 ） or 10 mg anisodamine injection （control group, n = 150）. The pain intensity was estimated by the VAS scores before and after the injection, meanwhile adverse reactions were also recorded. The results showed that the pain intensity was relieved significantly after 1 h of the injection in both groups（P 〈0. 01 ）. The effective rate of phloroglucinol was 84. 1% （126/150）, while that of anisodamine was 80. 0% （120/150）. The adverse reactions of treatment group were lower than that of control group （ all P 〈 0. 01 ）. The results indicate that phloroglucinol can effectively relieve abdominal pain caused by acute gastroenteritis with safety.

关 键 词：间苯三酚 腹痛 

分 类 号：R57[医药卫生—消化系统]