钼靶对乳腺癌诊断价值的Meta分析  

Meta analysis of diagnostic value of mammography for breast cancer

作　　者：王文娟 张旭东[2] 王润华[3] 

机构地区：[1]成都市妇女儿童中心医院,成都610091 [2]四川省疾病预防控制中心,成都610041 [3]重庆医科大学公共卫生学院卫生统计教研室,400016

出　　处：《重庆医学》2012年第14期1389-1391,共3页Chongqing medicine

摘　　要：目的利用Meta分析对钼靶诊断乳腺癌的价值进行系统综合评价。方法收集1990～2010年国内、外公开发表的关于钼靶诊断乳腺癌的原始文献,并按照制定的评价标准进行筛选,采用固定效应模型、随机效应模型和综合接受者工作特征曲线(SROC)分析方法,综合评价钼靶诊断乳腺癌的准确性。结果钼靶对乳腺癌诊断的合并灵敏度为84.03%(95%CI:82.04%～86.01%),合并特异度为77.59%(95%CI:72.89%～82.28%),合并后的诊断比值比(DOR)为15.05(95%CI:10.32%～21.95%);SROC曲线下面积(AUC)为0.874,诊断试验准确性指标(TPR)为81.62%。结论钼靶对乳腺癌的诊断具有较高的准确性,可作为乳腺癌筛查和诊断的一种较好的影像学方法。Objective To apply Meta analysis to process a systematic comprehensive evaluation on the diagnostic value of mammography（MG） for breast cancer.Methods The original literature published in home and abroad on the MG diagnosis of breast cancer from 1990 to 2010 were collected and screened according to the assessment standard.The fixed-effects model,random-effects model and summary receiver operating characteristic curve（SROC） were used to evaluate the accuracy of the mammography for diagnosing breast cancer.Results The pooled sensitivity of MG for diagnosing breast cancer was 84.03%（95% CI：82.04%-86.01%）,the pooled specificity was 77.59%（95% CI：72.89%-82.28%）,and the pooled diagnostic odds ratio（DOR） was 15.05（95%CI：10.32%-21.95%）.The area under the SROC curve was 0.874,the true positive rate（TPR） was 81.62%,which represented the accuracy index of SROC.Conclusion MG has higher accuracy on diagnosis of breast cancer,which is a better imageological method for diagnosis breast cancer.

关 键 词：乳房X线摄影术 乳腺肿瘤 META分析 

分 类 号：R737.9[医药卫生—肿瘤]