18氟-脱氧葡萄糖双探头符合线路断层显像在39例乳腺癌术前诊断中的应用  

Application of 18F-FDG coincidence SPECT/CT detection imaging in preoperative diagnosis of 39 cases of breast cancer

作　　者：刘永[1] 陆武[1] 宋长祥[1] 杜鹏[1] 

机构地区：[1]江苏省连云港市第一人民医院核医学科,222002

出　　处：《重庆医学》2012年第13期1293-1294,1296,F0003,F0004,共5页Chongqing medicine

摘　　要：目的探讨应用18氟-脱氧葡萄糖(18F-FDG)双探头符合线路断层显像(SPECT/CT)在乳腺癌术前诊断中的价值。方法选择2008年1月至2011年5月该院收治的临床疑诊乳腺癌的女性患者39例行18 F-FDG双探头符合线路SPECT/CT检查,诊断结果与病理检查结果对照,所得数据进行统计学分析。结果 39例乳腺肿块定性诊断的灵敏度、特异度、准确率分别为83.33%(25/30)、66.67%(6/9)、79.49%(31/39);34枚可疑转移淋巴结诊断的灵敏度、特异度、准确率分别为86.21%(25/29)、60.00%(3/5)、82.35%(28/34);4例患者发现远处转移,准确率为100%(4/4)。结论 18 F-FDG双探头符合线路SPECT/CT在乳腺癌术前诊断、分期等具有较高的准确性,为乳腺癌术前较好的无创性检查方法。Objective To explore the clinical value of 18F-fluorodeoxyglucose（18F-FDG）coincidence single-photon emission computed tomography/computer tomography（SPECT/CT）detection imaging for preoperative diagnosis of breast cancer.Methods Total 39 suspected patients with breast cancer were examined by 18F-FDG coincidence SPECT/CT detection and the results were compared with the pathological results.The sensitivity,specificity and the accuracy were calculated and analyzed respectively.Results Compared with pathological results,the sensitivity,specificity and the accuracy of 18F-FDG coincidence SPECT/CT detection for breast cancer were 83.33%（25/30）,66.67%（6/9）and 79.49%（31/39）respectively.To 34 breast cancer patients,the sensitivity,specificity and accuracy of lymph node metastasis were 86.21%（25/29）,60.00%（3/5）and 82.35%（28/34）respectively.Four cases were found metastasis in other organs and the accuracy was 100.00%（4/4）.Conclusion 18F-FDG SPECT/CT coincidence detection imaging has a perfect specificity and a considerable sensitivity in the early detection and staging for breast cancer,which is a useful noninvasive method for detecting breast lesions and metastasis lesions before treatment.

关 键 词：氟脱氧葡萄糖F18 体层摄影术 发射型计算机 单光子 乳腺肿瘤 淋巴结 

分 类 号：R737.9[医药卫生—肿瘤]