上皮性卵巢癌脑转移的现状分析  

The Current Situation of Brain Metastasis from Epithelial Ovarian Cancer

作　　者：张莉[1] 郝权[1] 

机构地区：[1]天津医科大学附属肿瘤医院妇瘤科,天津市肿瘤防治重点实验室,天津市300060

出　　处：《中国肿瘤临床》2012年第10期741-744,748,共5页Chinese Journal of Clinical Oncology

摘　　要：脑部是上皮性卵巢癌转移的少见部位,但近20年来发生率有所提高。多数患者以头痛症状就诊,诊断依赖于CT或MRI影像学检查。目前尚无一个统一的治疗规范,采取手术和放化疗在内的综合治疗可以使患者受益。特别对于单发脑转移灶者,以手术为主的综合治疗可以改善患者预后。立体定向放疗的应用为该治疗提供了新的前景。该病的预后差,相关预后因素尚有争议,目前一致认为患者一般情况良好和未合并颅外病灶有利于预后。Brain is considered an uncommon metastatic site for epithelial ovarian cancer. The incidence has increased during the last two decades. Most patients suffer from headache as the disease relapses at brain.The diagnosis is based on CT or MRI results. Now there is no uniform therapy options. The multimodality treatment including neurosurgery, radiotherapy and chemotherapy benifit the patients with brain metastasis. Especially for those patiens with single metastases, neurosurgery combined with other treatments can improve prognosis. Then a prospect arises up with the application of stereotactic radiosurgery. The disease has a poor prognosis. Several prognostic factors are still being discussed today. But only a high performance status and the absence of an extra cranial disease at the time of CNS relapse have been accepted throughout the current literature as having a significant positive impact on survival.

关 键 词：上皮性卵巢癌 脑转移 诊断 治疗 预后 

分 类 号：R737.31[医药卫生—肿瘤]