肿瘤患者PICC导管相关性感染影响因素调查分析  

Study on risk factors for PICC catheter-related infections in cancer patients

作　　者：马晓燕[1] 高玉芳[1] 魏丽丽[1] 张宏岩[1] 陈伟芬[1] 房芳[1] 池小锋[1] 黄倩[1] 

机构地区：[1]青岛大学医学院附属医院护理部,山东青岛266003

出　　处：《中华医院感染学杂志》2012年第11期2290-2292,共3页Chinese Journal of Nosocomiology

基　　金：山东医药卫生科技发展计划项目(2009HZ024)

摘　　要：目的探讨肿瘤患者PICC导管相关性感染影响因素,分析病原菌种类,为预防感染及临床合理用药提供依据。方法前瞻性追踪373例留置PICC肿瘤患者,分析PICC导管相关性感染的影响因素,并进行细菌学培养。结果 373例留置PICC肿瘤患者的总导管留置时间为40 547导管日,发生PICC导管相关性感染46例,感染率1.13/1000导管日;季节、导管维护周期、导管移动、机体免疫功能为PICC导管相关性感染的危险因素,导管穿刺技术为保护因素;感染病原菌分别为凝固酶阴性葡萄球菌、表皮葡萄球菌、清酒假丝酵母菌、沃氏葡萄球菌。结论使用赛丁格穿刺技术,提高夏季导管维护频次,导管维护标准化及增强患者机体免疫功能,可以降低肿瘤患者PICC导管相关性感染的发生。OBJECTIVE To explore the risk factors for PICC catheter-related infections in cancer patients and analyze the species of pathogenic bacteria so as to provide bases for the prevention of infections and the reasonable use of antibiotics.METHODS Prospective following-up of 373 cases of cancer patients with PICC was performed,the related factors for the infections were analyzed and the bacteriologic culture was performed.RESULTS The total indwelling time of 373 cancer patients with PICC was 40,547/days and the PICC catheter-related infections occurred in 46 cases with the infection rate of 1.13 per 1000 catheter-days;season,catheter maintenance period,local dressing condition and patient＇s immunity were the risk factors for PICC catheter-related infections,and the catheter insertion technique was the protective factor;the pathogenic bacteria causing infections included coagulase-negative Staphylococci,S.epidermidis,Candida sake and S.warneri.CONCLUSION To use seldinger puncture technique,increase the frequency of the catheter maintenance in summer,make catheter maintenance standardized and the improve the patient＇s immunity can decrease the incidence of PICC catheter-related infections in cancer patients.

关 键 词：经外周静脉置入中心静脉导管 导管相关性感染 肿瘤患者 

分 类 号：R730.231[医药卫生—肿瘤]