正畸牙移动致牙根吸收对龈沟液中牙本质涎磷蛋白及涎蛋白表达的影响  

Influence of Root resorption caused by orthodontic tooth movement on GCF DSPP, DSP expression

作　　者：林锦辉[1] 

机构地区：[1]海南省中医院口腔科,海南省海口570203

出　　处：《中国基层医药》2012年第8期1137-1138,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的探讨正畸牙移动致牙根吸收对龈沟液中牙本质涎磷蛋白（DSPP）、牙本质涎蛋白（DSP）表达的影响。方法将67例正畸患者按照不同力值将其分为观察组与对照组，观察组为过大力值（300g）组，对照组为正常力值（30g）组，对两组患者1—12周龈沟液中DSPP、DSP表达情况进行检测。结果观察组DSPP、DSP表达明显高于对照组，两组均在7—9周表达增加，观察组灰阶分别为（232315±5437）、（487876±4374）、（287673±5642），对照组灰阶为（212147±2346）、（176565±5327）、（134323±2315）；并在10周后出现降低，观察组10周以及11周灰阶为（394532±4326）、（287674±3235）；对照组分别为（87876±4323）、（76534±3564），11周均较10周有明显降低。结论在牙根吸收过程中龈沟液中DSPP、DSP表达变化可能早于X线结果以及临床表现，可能作为正畸牙移动致牙根吸收检测的早期指标。Objective To investigate the influence of root resorption caused by orthodontic tooth movement, on gingival crevicular fluid （GCF） dentin sialophosphoprotein, DSPP, dentin sialoprotein, DSP expression. Methods 67 patients admitted to hospital orthodontic patients as the clinical study, and according to different power values were divided into experimental group and control group, which had great value for the experimental group（300g） group and control group value for the normal force （30g） group, the two groups one week 12 weeks of its GCF DSPP, DSP expression were detected. Results In the observation group DSPP,DSP expression was significantly higher than that in the control group,two groups of patients were in 7 -9 weeks demonstrated increased, the observation group were （232 315 ± 5437） gray, （487 876 ± 4374）, （287 673 ± 5642）, （212 147±2346） control group of gray scale, （ 176 565 ±5327） ,（134 323 ± 2315）;and in 10 weeks after the reduction, the observation group lO weeks and 11 weeks, （ 394 532 ± 4326 ）, （ 287 674 ± 3235 ） ; the control group were （ 87 876 ± 4323 ）, （ 76 534 ± 3564 ）, 10 week 11 weeks were significantly reduced. Conclusion In the process of root resorption in GCF DSPP, DSP changes in expression levels may be earlier than the X-ray results and the clinical manifestations, as it may cause root resorption of orthodontic tooth movement in the early detection of a target.

关 键 词：正畸 牙根吸收 牙本质涎磷蛋白 牙本质涎蛋白 

分 类 号：R783.5[医药卫生—口腔医学]