美沙酮维持治疗123例基本情况分析  

Analysis of the basic condition of 123 patients on methadone mainterance treatment

作　　者：谈成文[1] 王士梅[1] 尹良爽[2] 唐炜超[3] 郭小蕾[1] 

机构地区：[1]淮南市第四人民医院,安徽省淮南232052 [2]安徽医科大学 [3]安徽省精神卫生防治中心精神科

出　　处：《中国基层医药》2012年第8期1158-1159,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的观察美沙酮维持治疗（MMT）药物剂量和参加MMT治疗者的依从性。方法对某门诊截至2010年7月31日在治且服药1个月以上的69例阿片类药物成瘾者及44例脱失患者的相关情况进行统计分析。结果患者的尿检结果与剂量之间差异无统计学意义（χ2=1．427，P=0．232），但尿检阳性率与入组次数呈显著相关（r=0．523，P=0．000）。治疗中脱失原因主要是违法犯罪，违法犯罪是影响MMT依从性、导致脱失的主要原因。结论MMT维持剂量的使用应个体化。Objective To observe the dose of methadone and the compliance of patients to the methadone maintenance treatment（MMT）. Methods We analyzed the status of 69 patients who were addicted to opiate medication and 44 patients who dropped out in our clinic until July 31,2010. Results There was no significant relationship between patients＇ urine test and the dose. Crime caused the patients who dropped out. The percentage of positive urine did not decline as the dose increased, but the rate of patients who dropped and the number of positive urine test showed a significant correlation（ r = 0. 523 P = 0. 000 ）. Crime was the main reason that affected the compliance to MMT and caused dropping out. Conclusion The use of MMT dose should be individualized.

关 键 词：海洛因依赖 美沙酮 依从性 

分 类 号：R749.64[医药卫生—神经病学与精神病学]