苯甲醛缩氨基硫脲类化合物的无溶剂合成  

The solvent-free synthesis of benzaldehyde thiosemicarbazone derivatives

作　　者：周艳青[1] 伍家卫[1] 吕维华[1] 

机构地区：[1]兰州石化职业技术学院石油化学工程系,甘肃兰州730060

出　　处：《应用化工》2012年第5期914-915,919,共3页Applied Chemical Industry

基　　金：甘肃省省属高校基本科研业务费资助项目甘财教(2009-192)

摘　　要：以液体苯甲醛和N4-苯基氨基硫脲为原料,浓盐酸作催化剂,室温条件下,在无溶剂条件下合成了4个苯甲醛缩氨基硫脲类化合物。产品经元素分析、红外光谱与核磁共振氢谱表征,确定为目标化合物。结果表明,无溶剂条件下的反应在2 h内产率达到90%,是合成该类化合物高产、低耗、绿色、环保的好方法。The benzaldehyde thiosemicarbazone derivatives are synthesized under solvent-free condition at room temperature.The reaction only needs 2 h to proceed catalyzed by concentrated hydrogen chloride（HCl）,and the yields of the product reach 90%.The structure of these compounds are characterized by elemental analysis,IR and 1H NMR.It＇s clear,that the solvent-free method is a high yields,low consumption green and environmental protection for the synthesis of this kind of fine chemicals.

关 键 词：苯甲醛 缩氨基硫脲 无溶剂合成 

分 类 号：TQ031[化学工程] O621.3[理学—有机化学]