TAG方案治疗老年急性髓系白血病  

TAG in the treatment of elderly patients with acute myeloid leukemia

作　　者：刘红艳[1,2,3] 郭静明 冉昌丽[1,2,3] 韩丹壘 叶松[1,2,3] 

机构地区：[1]三峡大学第一临床医学院 [2]宜昌市中心人民医院血液科 [3]三峡大学肿瘤研究所,湖北宜昌443003

出　　处：《临床血液学杂志》2012年第3期309-311,共3页Journal of Clinical Hematology

摘　　要：目的:探讨小剂量吡柔比星、阿糖胞苷和重组人粒细胞集落刺激因子组成的TAG化疗方案治疗老年人急性髓系白血病(AML)的疗效和不良反应。方法:老年AML初治31例,采用TAG化疗方案诱导及巩固治疗。结果:完全缓解15例,部分缓解9例,无效7例,总有效率77.4%。结论:TAG方案治疗老年AML缓解率高,不良反应轻,患者耐受性好,尤其在具有预后良好和预后中等染色体核型组疗效更明显。Objective：To investigate the efficacy and adverse reactions of TAG consisting of pirarubicin,cytarabine,and recombinant human granulocyte colony-stimulating factor in elderly acute myeloid leukemia. Method：Thirty-one cases of elderly acute myeloid leukemia patients were treated with TAG as induction chemotherapy and consolidation therapy. Result：Fifteen cases got CR,9 cases PR,7 cases NR.The total efficiency was 77.4%. Conclusion：Elderly AML patients treated with TAG got high remission rate and low adverse reactions.All the patients were well tolerated,especially in the patients with good or middle prognosis chromosome abnormalities.

关 键 词：白血病 髓系 急性 TAG方案 化疗 疗效 

分 类 号：R733.71[医药卫生—肿瘤]