多发性硬化与病毒感染研究进展  

Progress in Multiple Sclerosis and Virus Infection

作　　者：王雅泉[1] 魏麓云[1] 

机构地区：[1]南华大学第二附属医院神经内科,湖南衡阳421001

出　　处：《现代生物医学进展》2012年第10期1995-1997,1991,共4页Progress in Modern Biomedicine

摘　　要：多发性硬化发病机制复杂,病毒感染在其发病中可能起着举足轻重的作用,目前多项研究支持他们之间的关联性;分子模拟、免疫调节网络的失调、表位扩展、旁路激活、超抗原激活和直接细胞损伤等是病毒感染导致多发性硬化发病的主要机理。本文就相关研究进行综述。The pathogenesis of multiple sclerosis is complex,virus infection in the disease may play a significant role.At present many studies support the correlation between them;Molecular mimicry,the imbalance of immune regulatory network,epitope spreading,bypass activation,superantigens direct cellular activation and direct cellular damage is the main pathogenesis for virus infection leading to multiple sclerosis.This paper reviewed the related progress in recent years.

关 键 词：多发性硬化 病毒感染 发病机制 

分 类 号：R744.51[医药卫生—神经病学与精神病学]