睡眠纺锤波在植物状态病人预后判别中的价值研究  

Predict Recovery of Consciousness in Patients with Vegetative State:the Role of Sleep Spindles of EEG

作　　者：景芸芸[1] 徐晓霞[1,2] 康晓刚[1] 蒋斌[1] 江文[1] 

机构地区：[1]第四军医大学西京医院神经内科,陕西西安710032 [2]武警陕西省总队医院神经内科,陕西西安710032

出　　处：《现代生物医学进展》2012年第11期2077-2079,共3页Progress in Modern Biomedicine

基　　金：学科助推计划;重大项目(xjzt09z07)

摘　　要：目的:探讨脑电图睡眠纺锤波在植物状态病人预后判别中的价值。方法:在长程脑电监测下观察植物状态病人的睡眠纺锤波,与其意识恢复进行相关性分析,并预测患者意识恢复的敏感性、特异性及准确性。结果:28例患者中,12例有纺锤波,其中9例意识恢复;16例无纺锤波患者中,14例未恢复意识。纺锤波的有无与患者意识恢复有相关性,P值<0.01。脑电图睡眠纺锤波对植物状态患者意识恢复判断的敏感性(83.25%)、特异性(81.82%)、准确性(82.14%)。结论:脑电图睡眠纺锤波可较准确预测植物状态患者的意识恢复能力,可作为临床评估植物状态患者意识恢复能力的辅助方法。Objective： The purpose of this study is to examine the predicting role of sleep spindles of EEG in the recovery of con-sciousness in patients with vegetative state.Methods： We observed the spindles of EEG under continuou s electroencephalogram in 28 patients with vegetative state,respectively.Correlation between spindles of EEG and consciousness recovery was analyzed.And then,sensitivity,specificity and accuracy were calculated on the presence of spindles and recovery of consciousness.Results： Of 28 patients enrolled in the study,11 of them recovered consciousness,and 17 of them did not recover consciousness.Spindles of EEG were observed in 12 patients and 9 of them recovered consciousness.While spindles of EEG did not observe in 16 patients and 10 of them not recovered consciousness.These data indicate that the presence of spindles of EEG was a strong positive prognostic factor for consciousness recovery.The sensitivity,specificity and accuracy of the presence of spindles of EEG were 83.25%,81.82%,82.14% respectively.Conclusions： The presence of spindles of EEG is a good positive factor for the prognosis of recovery of consciousness in vegetative state patients.

关 键 词：脑电图睡眠纺锤波 植物状态 意识 

分 类 号：R741[医药卫生—神经病学与精神病学]