内镜下逆行胰胆管造影置放胆道支架治疗恶性梗阻性黄疸98例疗效分析  

Analysis of the Effect on Malignant Biliary Obstruction Treated by Endoscopic Biliary Stent Insertion in 98 cases

作　　者：张伟星[1] 陈颖[2] 段晓燕[3] 李楠[3] 宛新建[1] 

机构地区：[1]上海交通大学附属第一人民医院消化内科,上海200080 [2]上海交通大学附属瑞金医院内分泌研究所,上海200025 [3]上海交通大学附属新华医院消化内科,上海200092

出　　处：《现代生物医学进展》2012年第11期2080-2084,共5页Progress in Modern Biomedicine

基　　金：教育部博士点基金(2-0902)

摘　　要：目的:探讨内镜下逆行胰胆管造影置放胆道支架对恶性胆道梗阻的疗效及并发症的防治。方法:选择2008年2月至2011年9月我院收治的无法手术切除或不愿手术的恶性胆道梗阻患者98例,通过放置内置支架引流观察其操作成功率、支架通畅期和退黄效果、并发症发生情况及其防治效果和患者生存期等。结果:98例患者中有88例成功通过置入胆道内置引流管,成功率为89.8%,并发症发生率为11.22%,所有成功患者术后1周黄疸明显减退,支架平均通畅期137天,患者平均生存期为163天。结论:行胆道内置支架引流创伤小,并发症少,通畅性能好,可持久有效地控制黄疸,有效缓解病情,改善全身情况,明显延长恶性胆道梗阻患者的生存期。Objective： To study the clinical value and therapeutic effect of encoscopic retrograde cholangio pancreatography（ERCP） on malignant obstructive jaundice.Methods： By studying on the drainage by using biliary stent built in by ERCP in 98 cases of patients with malignant biliary obstruction,which was impossible to cut off or the patients was not willing to take the operation from Feb.2008 to Sept..2011,observe their success rate,the jaundice-reduce effect,the incurred complications,prevention effect of complications,stent pa-tency period and survival period.Results： 88 patients were successfully placed by ERCP biliary drainage tube,and the success rate was 89.8%;the jaundice of all the patients with the successful operation had decreased significantly（P0.05） after a week;the average patency period of stents was 137days,and the average survival period of patients was 163 days.Conclusion： Drainage with the biliary stents built in by ERCP got less injure and complications,good unobstructed performances,and could effectively and lastingly alleviate the patients＇ serious illness,control the Jaundice,improve their general conditions and extent their survival period.

关 键 词：内镜下逆行胰胆管造影 恶性梗阻性黄疸 胆道支架 并发症的防治 

分 类 号：R735[医药卫生—肿瘤]