宫颈癌综合治疗预后因素的分析  

Analysis of Prognostic Factors of Patients with Cervical Cancer after Synthetic Therapy

作　　者：蒋骞[1] 周业琴[1] 雷静[1] 

机构地区：[1]川北医学院附属医院,四川南充637000

出　　处：《航空航天医学杂志》2012年第6期645-647,共3页Journal of Aerospace medicine

摘　　要：目的:通过随访103例各期宫颈癌患者,观察综合治疗以后的3年总生存率,探讨不同临床病理因素对宫颈癌预后的影响。方法:收集2005-01～2007-01间103例接受根治性或辅助性放、化疗的宫颈癌患者的临床及随访资料,分析影响预后的因素。结果:随访期间失访4例,平均随访时间32.5个月,失访率3.88%1,03例中有31例死亡。全组患者3年总生存率(Overall survival rate,OS)为71.6%。单因素分析显示:临床分期、肿瘤直径、病理类型、宫旁受浸、盆腔淋巴结转移与宫颈癌预后相关(P<0.05)。多因素分析显示:临床分期、肿瘤直径、病理类型、盆腔淋巴结转移显著影响宫颈癌预后(P<0.05)。结论:临床分期、病理类型、肿瘤直径、盆腔淋巴结转移是影响宫颈癌预后的独立因素。Objective：To observe the 3-year overall survival rate after synthetic therapy in 103 patients with cervical cancer by follow-up and to explore different clinicopathologic factors of the prognosis of cervical cancer.Methods：Collect the follow-up and clinical data of 103 patients who received radical or adjuvant chemoradiotherapy for cervical cancer from January 2005 to January 2007.Analysis of prognostic factors.Results：During follow-up period,4 patients were missed and the average follow-up time was 32.5 months.The lost to follow-up rate was 3.88%.31 patients died in 103 case and the 3-year overall survival rate was 71.6%.Univariate analysis showed that： the clinical stage、the tumor size、 the histologic type、parametrial invasion、pelvic lymph node metastasis relate to the prognosis of cervical cancer（P0.05）.Multi-factor analysis showed that the clinical stage、 the tumor size、the histologic type、pelvic lymph node metastasis significantly affected the prognosis of cervical cancer（P0.05）.Conclusions：The clinical stage、the tumor size、the histologic type、pelvic lymph node metastasis were independent factor affecting the cervical cancer prognosis.

关 键 词：宫颈癌 预后 综合治疗 

分 类 号：R737.33[医药卫生—肿瘤]