神经重症监护病房卒中相关性肺炎临床特点及危险因素分析  

Analysis on Clinical Characteristics and Risk Factors of Stroke-associated Pneumonia in Neurological Intensive Care Unit

作　　者：王立志[1] 罗伟良[1] 黄晓东[1] 

机构地区：[1]广东省惠州市中心人民医院神经内科,广东惠州516001

出　　处：《航空航天医学杂志》2012年第6期685-687,共3页Journal of Aerospace medicine

摘　　要：目的:探讨神经重症监护病房急性卒中患者卒中相关肺炎(SAP)的临床特点及危险因素。方法:回顾性分析2011-01～2011-12于神经重症监护病房住院的急性卒中患者SAP的临床特点,分析SAP的危险因素。结果:共144例急性卒中患者入选8,1例(56.3%)发生SAP,细菌培养以金黄色葡萄球菌、肺炎克雷伯菌、铜绿假单胞菌为主。单因素分析显示房颤、吸烟、低蛋白血症、意识障碍、吞咽功能障碍、脑干卒中、入院时美国国立卫生研究院卒中量表(NIHSS)评分与SAP有关。多因素分析表明吞咽功能障碍、意识障碍、低蛋白血症、吸烟是SAP发生的独立预测因素。结论:神经重症监护病房SAP发生率高,吞咽功能障碍、意识障碍、低蛋白血症、吸烟是SAP发生的独立预测因素。Objective：To investigate the clinical characteristics and risk factors of stroke-associated pneumonia（SAP） in patients with acute stroke who were admitted to Neurological Intensive Care Unit.Methods：We retrospectively investigated the acute stroke patients treated in Neurological Intensive Care Unit of HuiZhou Municipal Central Hospital between January 2011 and December 2011.The clinical characteristics and risk factors of SAP were discussed.Results：144 acute stroke patients were enrolled and 81cases（56.3%） were with SAP.Staphylococcus aureus,Klebsiella pneumoniae and Pseudomonas aeruginosa were prevelant.In univariate analysis,atrial fibrillation,smoking,hypoproteinemia,conscious disturbance,dysphagia,stroke involved brainstem and National Institute of Health Stroke Scale score on admission were associated with SAP.In multivariate analysis,dysphagia,conscious disturbance,hypoproteinemia,smoking were independent predictors of SAP.Conclusions：The incidence rate of SAP is quite high in acute stroke patients admitted to Neurological Intensive Care Unit.Dysphagia,conscious disturbance,hypoproteinemia,smoking are independent predictors of SAP.

关 键 词：脑卒中 肺炎 危险因素 

分 类 号：R743.3[医药卫生—神经病学与精神病学]