切缘阴性宫颈上皮内瘤变患者术后随诊情况分析  

Evaluation of the follow-up results of clear margine patients with cervical intraepithelial neoplasia after surgical treatment

作　　者：金梅[1] 施美满 费小阳[1] 

机构地区：[1]浙江省金华市人民医院妇产科,浙江金华321000

出　　处：《中国现代医生》2012年第14期143-145,共3页China Modern Doctor

基　　金：吴阶平医学基金会临床科研专项资助基金(320.6750.09092)

摘　　要：目的探讨280例切缘阴性宫颈上皮内瘤变患者的术后随诊情况及其影响因素。方法回顾性分析2008年4月1日～2009年5月30日我院收治的280例CIN接受手术且切缘阴性患者的临床资料、随访情况,将所有随访患者分为严密随访、定期随访、非正规随访3组,有效随访为严密随访+定期随访。结果 280例患者中,有效随诊率为57.1%(160/280)。有效随诊患者中,年龄≥45岁的患者有效随诊率[46.5%(59/127)]明显低于<45岁者[66.0%(101/153);P<0.05];子宫全切除术者的有效随诊率[36.0%(9/25)]低于宫颈LEEP术和宫颈锥切术患者的有效随诊率[57.0%(90/158)、62.9%(61/97)],差异有统计学意义;术前诊断CINⅠ级患者的有效随诊率[38.2%(13/34)]明显低于CINⅡ级的有效随诊率[53.2%(75/141),P<0.05],同时CINⅠ级和CINⅡ级患者的有效随诊率低于CINⅢ级的有效随诊率[68.6%(72/105),P<0.05],差异有统计学意义。随诊中25例(12.7%)发现病变复发和进展。结论年龄、手术方式和术前CIN严重程度影响患者的有效随诊率。Objective To evaluate the follow-up results of patients with cervical intraepithelial neoplasia （CIN） after surgi- cal treatment. Methods A retrospective analysis of consecutive patients with CIN after surgical treatment between April 1st 2008 and May 30th 2009 and the follow-up of patients after surgical treatment were assessed. Results In the follow-up of patients with CIN after surgical treatment, the rate of effective follow-up was 57.1% （160/280）. Among them, the rate of follow-up was lower in patients over 45 years old, and in patients with initial hysterectomy; the rate of follow-up in pa- tients with CIN m was higher than in patients with CIN Ⅰ and CIN Ⅱ pre-operative. Conclusion The rate of follow-up is lower in patients with over 45 years old, in patients having initial hysterectomy and in patients of CIN Ⅰ and Ⅱ. The rate of follow-up is associated with age, surgical approach and CIN degree.

关 键 词：宫颈上皮内瘤样病变 妇科外科手术 随访研究 

分 类 号：R737.33[医药卫生—肿瘤]