分子识别和生物分离研究的现状及发展趋势  

Current trends in molecular recognition and bioseparation

作　　者：曾庆冰[1] 许家瑞[1] 俞耀庭[2] 

机构地区：[1]中山大学材料科学研究所,广东广州510275 [2]南开大学分子生物研究所,天津300071

出　　处：《国外医学（生物医学工程分册）》2000年第1期18-23,共6页Foreign Medical Sciences(Biomedical Engineering Fascicle)

摘　　要：生物分子识别应用于分离科学使固相配基设计和亲和层析技术如雨后春笋般发展起来。本文着重列举各种用于生物分子分离的固定配基设计。介绍了蛋白特异性配基、亲和识别标记物 ,及在固定配基识别大分子技术基础上发展起来的亲和分析方法。Molecular recognition has stimulated an explosion of soid phase ligand designs and affinity chromatographic applications.This article focuses on types of immobilized ligands designed for biomolecular separation.Protein specific ligands,affinity tags and some analytical methods that have been spawned from the success of affinity chromatography are discussed.The use of phage display methods to obtain affinity matured ligands as separation tools is also mentioned.

关 键 词：分子识别 固定配基 生物分离 研究 发展趋势 

分 类 号：Q503[生物学—生物化学]