深圳市龙岗区流动育龄妇女HPV感染率及型别分布的分析  

HPV infection rate and its subtype distribution in migrating women of childbearing age in Longgang

作　　者：吴志丽[1] 迟绍琴[1] 徐乐凤 

机构地区：[1]深圳市龙岗区计划生育服务中心妇科,广东深圳518172

出　　处：《中国性科学》2012年第5期25-27,共3页Chinese Journal of Human Sexuality

摘　　要：目的:调查深圳市特定人群的人乳头瘤病毒(Human papillomavirus,HPV)感染率及亚型分布,为预防HPV感染和宫颈癌防治提供依据。方法:采用PCR-PEX-MS分型检测技术对龙岗区流动育龄妇女进行HPV检测,并对各亚型进行比较分析。结果:5260例调查标本中HPV感染364例,阳性率为6.92%,其中单一感染率为5.87%,双重感染为0.84%,多重感染为0.21%。共检出亚型466次。结论:调查人群HPV感染率低于国内其他报道,高危型以HPV52,16型为主,现有疫苗并非对所有人群有效。Objectives： To investigate HPV infection rate and HPV subtype distribution in the migrating women of child- bearing age in Shenzhen with an aim to provide reference for HPV prevention and uterine cervical cancer treatment. Methods： The migrating childbearing age women in Longgang District were examined for HPV with the technique of PCR- PEX- MS gene - chip. Their subtypes were analyzed and compared. Results： Of 5260 women investigated, 364 were HPV positive with a posi- tive rate of 6.92% ; the single type infection rate was 5.87%, the double type infection rate 0.84%, and the multiple type infec- tion rate 0.21%. HPV subtypes were detected 466 times. Conclusion： The HPV infection rate of the investigated population was lower than that of other domestic reports. HPV52 and HPV16 were shown to be the high - risk subtypes. The existing vaccine a- gainst HPV was not effective to all people.

关 键 词：流动育龄妇女 人乳头瘤病毒 亚型 

分 类 号：R737.33[医药卫生—肿瘤]