前列腺癌预后相关分子标志物  

Prostate Cancer Prognostic Molecular Markers

作　　者：张年凤[1] 吴新刚[1] 李光[2] 

机构地区：[1]岳阳职业技术学院医学基础部,湖南岳阳414000 [2]中南大学湘雅附二医院脊柱外科,湖南长沙410000

出　　处：《岳阳职业技术学院学报》2012年第2期102-105,共4页Journal of Yueyang Vocational and Technical College

摘　　要：前列腺癌作为男性生殖系统好发的恶性肿瘤,其发生及预后的判断直接关系到男性的生存健康。传统的前列腺癌预后评价指标,如TNM分期、Gleason评分和PSA表达水平等,对临床预后判断有一定意义。但近些年大量分子标志物的发现和应用为前列腺癌的预后评估提供了更可靠、更准确的依据。文章对与前列腺癌发生、转移及血管生成等相关的分子标志物作一综述。Prostate cancer is the male reproductive system usual malignant tumor,the occurrence and prognosis is directly related to the male survival and health.The traditional prostate cancer prognosis evaluation indicators,such as TNM stage,Gleason score and PSA expression levels,have some significance in clinical.But in recent years,the discovery and application of many molecular markers for prostate cancer prognosis assessment provides more reliable,more accurate basis.Now the occurrence,metastasis and angiogenesis related molecular markers of prostate cancer are reviewed in this paper.

关 键 词：前列腺癌 预后评估 分子标志物 

分 类 号：R737[医药卫生—肿瘤]