无创颅内压及脑灌注压监测在高血压脑出血中的临床应用  

Clinical Application of Noninvasive Intracranial Pressure and Cerebral Perfusion Pressure Monitoring in Treating the Patients with Hypertensive Intracerebral Hemorrhage

作　　者：张文德[1] 张湘[1] 邹志浩[1] 吴勤奋[1] 殷捷[1] 王建江[1] 郑玺[1] 莫拉丁[1] 

机构地区：[1]中国人民解放军第474医院神经外科,新疆乌鲁木齐830013

出　　处：《新疆医学》2012年第4期1-4,共4页Xinjiang Medical Journal

摘　　要：目的:探讨无创颅内压(NICP)、脑灌注压(CCP)监测在高血压脑出血手术前后变化的临床意义。方法:监测和比较60例高血压脑出血患者手术前后NICP、CCP的变化。结果:本组手术前后除10例NICP压力<26.6mmHg,CPP>124.3mmHg外,其余50例均有不同程度NICP增高与CPP降低。对于这些患者,根据监测结果进行相应的手术及综合治疗。手术前后NICP、CPP变化经统计学处理均有显著性差异(P<0.01和0.05)。术后随访6个月,并根据(Glasgow Outcome Scale)GOS标准评定治疗结果,其中有6例重残(10%),5例死亡(8.3%)。结论:对高血压脑出血患者手术前后施行NICP、CPP监测是提高诊断、指导用药、降低并发症和病死率,提高疗效的有力措施,具有重要临床应用价值。Objective： To elucidate the clinical significance of noninvasive intracranial pressure （NICP） and cerebral perfusion pressure （CPP） monitoring in patients with hypertensive intracerebral hemorrhage. Methods： It was a clinical study. NICP and CPP of 60 cases were continuously measured and analyzed before and after operation. Results In this group , 50 patients showed increased NICP and decreased CPP , and 10 cases with normal NICP（〈26.6mmHg） and CPP（ 〉 124.3mmHg）. According to monitored results of NICP and CPP, the relevant interventions, such as further operation or drug treatment, were performed. There were significant differences in NICP and CPP between before and after operation （P 〈 0.01 and 0.05）. According to GOS（ Glasgow Outcome Scale） ,there were 6 cases deformity （deformity rate was 10% ） and 5 cases death （ fatality rate was 8.3% ） after follow - up 6 months. ConClusion ： Continuous NICP and CPP monitoring before and after operation should be played an important role in the management of hypertensive intracerebral hemorrhage patients, in order to reduce complications and mortality, guide treatment, improve diagnosis and clinical efficacy.

关 键 词：无创颅内压 脑灌注压 监测 高血压脑出血 

分 类 号：R743.34[医药卫生—神经病学与精神病学]