学龄前儿童的听觉感觉记忆研究  

Study of auditory sensory memory in normal preschool children

作　　者：高延[1] 洪琦[1] 罗小杏[1] 蒋滔滔[1] 徐惠连[1] 姚小芳[1] 靳艳[1] 卓秀慧[1] 

机构地区：[1]深圳市宝安区妇幼保健院,广东深圳518133

出　　处：《中国儿童保健杂志》2012年第6期510-513,共4页Chinese Journal of Child Health Care

基　　金：深圳市科技计划项目(201003337)

摘　　要：【目的】使用听觉事件相关电位研究正常学龄前儿童的听觉感觉记忆功能。【方法】使用听觉oddball范式对30～72个月正常学龄前儿童给予纯音刺激,标准刺激和偏离刺激分别为1 000Hz和1 200Hz,二者出现概率分别为0.85和0.15。【结果】正常学龄前儿童出现明确的失匹配负波和晚辨别负波,主要分布在额中央区,平均潜伏期在170～175ms和450～500ms。左右半球在100～250ms时间窗内失匹配负波平均振幅未见显著差异。在F4点男性儿童较女性儿童振幅显著增高。【结论】学龄前儿童具有发育稳定的失匹配负波和晚辨别负波。男女性可能在学龄前期存在听觉感觉记忆加工差别。[Objective] To investigate the auditory sensory memory function of normal preschool children with auditory event-related potential. [Methods] The mismatch negativity（MMN）was obtained in preschool children ages ranged from 30 to 72 months in an oddball paradigm. Stimulus consisted of 1 000 Hz tones with 85 % probability as standard and 1 200 Hz with 15% probability as deviant. [Results] Pure tones elicited a strong MMN（peaking at about 1704175 ms） and a late discrimination negativity（peaking at about 450 - 500 ms）after stimulus onset mainly in the frontocentral area. There was no significant difference between the right and left hemisphere in the mean amplitude of 100 to 250 ms time-win- dow. [Conclusions] The MMN and late discrimination negativity are developmentally quite stable in preschool children. There are probably difference in auditory sensory memory processing between male and female preschool children.

关 键 词：事件相关电位 失匹配负波 儿童 学龄前 听觉感觉记忆 

分 类 号：R749.94[医药卫生—神经病学与精神病学]